[锌:一种必需微量营养素的概念]。

J Salgueiro, M Zubillaga, A Lysionek, M I Sarabia, G Calmanovici, R Caro, T De Paoli, A Hager, R Weill, J Boccio
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引用次数: 0

摘要

现在大家都知道锌是一种必需的微量营养素。尽管已有很多信息,但仍有许多问题有待研究。锌被肠道吸收,并通过白蛋白在血浆中运输,形成一个小的可交换池,即使在轻度缺乏的情况下也会迅速耗尽。锌对大约70种酶的活性和其他功能至关重要。因此,缺锌会产生大量的临床疾病,其症状可能从轻微到严重的功能障碍不等。这些问题可以通过膳食补充锌来纠正。缺乏一种可靠的方法来确定锌的营养状况,反映了金属推荐膳食摄入量的估算问题,特别是儿童、老年人和孕妇这一主要风险群体遇到的困难。虽然我们对锌毒性的了解很少,但众所周知,锌的毒性作用远远高于常规饮食和补充锌的饮食中所含的锌。因此,需要制定有效的战略,如在食品中添加适当的锌化合物,作为一种有吸引力的替代办法,以预防和(或)纠正这一重要元素的缺乏,并改善全体人口的健康和生活质量。
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[Zinc: concepts on an essential micronutrient].

It is now well known that zinc is an essential micronutrient. Even though much information is available, there are many points that remain to be studied. zinc is absorbed by the intestine and transported in the plasma by albumin, forming a small exchangeable pool, which is rapidly exhausted even in cases of mild deficiency. zinc is essential for the activity of about 70 enzymes among other functions. Therefore, zinc deficiency produces a great number of clinical disorders, the symptoms of which may range between mild up to serious dysfunctions. These problems are corrected by a dietary supplementation with zinc. The lack of a reliable method to determine the zinc nutritional status reflects the problem to estimate the metal recommended dietary allowances, which are difficulty met specially by children, old persons and pregnant women which constitute the main risk groups. Although our knowledge concerning zinc toxicity is scarce, it is well known that the amounts of zinc that produces toxic effects are much higher than those that are contained in regular diets as well as in diets supplemented with this metal. Therefore, the need of the development of effective strategies, like food fortification with proper zinc compounds, appears as an attractive alternative in order to prevent and/or correct the deficiency of this vital element and to improve the health and the life quality of the whole population.

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