【60岁以上成人贫血的病因学研究与诊断】。

Sangre Pub Date : 1999-12-01
J I Elejalde Guerra, J L Alonso Martínez, T Rubio Vela, C García Labairu, B Llorente, M Echegaray
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引用次数: 0

摘要

目的:贫血,特别是缺铁性贫血是一个世界性的健康问题,也是发展中国家最常见的营养缺乏问题。内科住院病人贫血的流行病学尚不清楚。患者和方法:在回顾性的基础上,我们研究了105例血红蛋白水平低于115 g/L的患者。分析患者的症状、贫血类型、病因、诊断方法、病理表现和输血计划。结果:平均血红蛋白77.8 g/L (SD 17.9)。与慢性疾病(CDA)相比,女性和IDA的贫血程度更深(p < 0.05),与可能诱发贫血的治疗药物无关(p < 0.01)。IDA是最常见的,其次是出血性贫血(HA)和CDA。在大多数病例中,发现潜在疾病的诊断程序是上消化道内窥镜检查,而CDA需要的诊断程序最多。上消化道贫血的种类、症状与内镜检查结果无相关性,而低消化道症状(出血、手指直肠检查异常)与结肠镜检查病理结果有直接关系(p < 0.05)。结论:IDA是内科诊断最多的贫血,其次是HA和ACD。临床症状与贫血类型相关性较差。在IDA中,上消化道内窥镜检查和下消化道检查是强制性的。我们建议50岁以上的患者进行结肠镜检查,而年轻人可以采用钡灌肠。
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[Etiological study and diagnosis of anemia in adults over 60 years of age].

Purpose: Anaemia especially iron deficiency anaemia (IDA) is a worldwide health problem and the most frequent nutritional lack in developing countries. The epidemiology of anaemia in hospitalized patients in Internal Wards is not well-known.

Patients and methods: On a retrospective basis we studied 105 patients with haemoglobin levels below 115 g/L. Symptoms, type of anaemia, causing disease, diagnostic procedures, pathologic findings and transfusional schedule were analyzed.

Results: Mean haemoglobin was 77.8 (SD 17.9) g/L. Anaemia degree was deeper in women (p < 0.05) and IDA comparatively with chronic disease (CDA) (p < 0.01) and it did not show relation with therapeutic agents which potentially induce anaemia. IDA was the most frequent followed by haemorrhagic anaemia (HA) and CDA. The diagnostic procedure which discovered an underlying disease in most of the cases was upper digestive tract endoscopy, and CDA needed the highest number of diagnostic procedures. There was not relationship between the sort of anaemia and symptoms due to upper digestive tract and endoscopic findings, however low digestive tract symptoms (bleeding and abnormal finger rectal examination) and pathologic findings in colonoscopy had a straight relation (p < 0.05).

Conclusions: IDA is the anaemia most frequently diagnosed in an Internal Medicine Department followed by HA and ACD. Clinical symptoms and the type of anaemia have poor correlation. In IDA upper digestive endoscopy as well as lower digestive tract examination is mandatory. We propose colonoscopy in patients aged more than 50-years whereas barium enema could be employed in younger people.

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