结构基因组学的蛋白质结构建模。

R Sánchez, U Pieper, F Melo, N Eswar, M A Martí-Renom, M S Madhusudhan, N Mirković, A Sali
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引用次数: 220

摘要

大多数蛋白质序列的形状将基于它们与实验确定的蛋白质结构的相似性来建模。在结构基因组学的背景下,讨论了目前蛋白质结构建模(利用基因和基因组信息)的作用、局限性、挑战和前景。
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Protein structure modeling for structural genomics.

The shapes of most protein sequences will be modeled based on their similarity to experimentally determined protein structures. The current role, limitations, challenges and prospects for protein structure modeling (using information about genes and genomes) are discussed in the context of structural genomics.

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Hardware and software Structural aspects of protein synthesis Starting off right Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy Protein structure modeling for structural genomics.
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