{"title":"多毛患者的性激素结合球蛋白水平:联合OCs的影响。","authors":"O F Giwa-osagie, M Levell","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Sex hormone binding globulin (SHBG) has been measured using an improved ammonium-precipitation method. SHBG has been measured in normal male and female subjects, and in hirsute subjects on and off combined oral contraceptives (OCs). SHBG concentrations in hirsute subjects were significantly lower than those of normal female subjects (P0.001). During treatment with OCs, SHBG concentrations rose significantly (P0.001). Among hirsute patients, there was no significant (P0.5) difference between the pretreatment SHBG concentrations of 'responders' and those of 'nonresponders.' During treatment, SHBG concentrations increased in both groups.</p>","PeriodicalId":84493,"journal":{"name":"Contraceptive delivery systems","volume":"3 2","pages":"155-60"},"PeriodicalIF":0.0000,"publicationDate":"1982-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sex hormone binding globulin levels in hirsute patients: the effect of combined OCs.\",\"authors\":\"O F Giwa-osagie, M Levell\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Sex hormone binding globulin (SHBG) has been measured using an improved ammonium-precipitation method. SHBG has been measured in normal male and female subjects, and in hirsute subjects on and off combined oral contraceptives (OCs). SHBG concentrations in hirsute subjects were significantly lower than those of normal female subjects (P0.001). During treatment with OCs, SHBG concentrations rose significantly (P0.001). Among hirsute patients, there was no significant (P0.5) difference between the pretreatment SHBG concentrations of 'responders' and those of 'nonresponders.' During treatment, SHBG concentrations increased in both groups.</p>\",\"PeriodicalId\":84493,\"journal\":{\"name\":\"Contraceptive delivery systems\",\"volume\":\"3 2\",\"pages\":\"155-60\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1982-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Contraceptive delivery systems\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Contraceptive delivery systems","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Sex hormone binding globulin levels in hirsute patients: the effect of combined OCs.
Sex hormone binding globulin (SHBG) has been measured using an improved ammonium-precipitation method. SHBG has been measured in normal male and female subjects, and in hirsute subjects on and off combined oral contraceptives (OCs). SHBG concentrations in hirsute subjects were significantly lower than those of normal female subjects (P0.001). During treatment with OCs, SHBG concentrations rose significantly (P0.001). Among hirsute patients, there was no significant (P0.5) difference between the pretreatment SHBG concentrations of 'responders' and those of 'nonresponders.' During treatment, SHBG concentrations increased in both groups.