[吸烟者、慢性阻塞性肺病和肺心病患者PEF的变化及临床意义]。

Guitang Huang, Zhengchang Fan, Jianqing Wang
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引用次数: 0

摘要

目的:了解吸烟者、慢性阻塞性肺病和肺心病患者PEF的变化及其临床意义。方法:对116例吸烟者、90例慢性阻塞性肺病(慢性支气管炎43例,肺气肿47例)和31例肺心病患者进行F-V曲线测定。选取的指标为FVC、PEF、V75、V50和V25。结果:吸烟者和慢性支气管炎患者的PEF%(实测值/预测值)均高于84%(即:百分比在正常范围内);肺气肿和肺心病患者分别为44%和32%,随病情严重程度降低。吸烟者和慢性支气管炎患者的[公式:见文本](%)为87.7%-89.7%(同样,百分比在正常范围内);肺气肿和肺心病患者分别为70.7%和41.9%,随病情加重而降低。用波速理论可以解释V75%比PEF%下降更明显的现象。结论:PEF%与[公式:见文](%)的降低程度有临床意义。
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[Change and clinical significance of PEF in smokers, COPD and cor pulmonale patients].

Objective: To understand the change and clinical significance of PEF in smokers, COPD and cor pulmonale patients.

Methods: The F-V curves were measured in 116 smokers, 90 COPD (43 with chronic bronchitis, 47 with emphysema) and 31 cor pulmonale patients in the ameliorated period. The indices selected were FVC, PEF, V75, V50 and V25.

Results: The PEF% (measured values/predicted values) in smokers and chronic bronchitis patients were higher than 84%(i.e. percentages being within the normal range); they were 44% and 32% in patients with emphysema and cor pulmonale respectively and decreased with the severity of disease. The [formula: see text] (%) in smokers and chronic bronchitis patients were 87.7%-89.7% (again, percentages being within the normal range); they were 70.7% and 41.9% in patients with emphysema and cor pulmonale respectively and decreased with the severity of disease. The phenomenon that decrease was more conspicuous in V75% than in PEF% could be explained with the wave-speed theory.

Conclusion: There is clinical significance in the degree of decrease in PEF% and [formula: see text] (%).

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