{"title":"核因子κ B在人腺癌癌细胞中的表达","authors":"Yao Chen, Ruixiang Li","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Nuclear factor kappa B is very important in cis-activation which regulates the expression of many genes. This study inquired into the mechanism of cancer cell metastasis.</p><p><strong>Methods: </strong>Immunohistochemical method was used for studying the expression of nuclear factor kappa B in cancer cells of human metastasized rectum adenocarcinoma.</p><p><strong>Results: </strong>Expressed nuclear factor kappa Bp65 was found in the cancer cells of peritumoral tissues and metastasized lymph nodes. The reaction product was located in the cytoplasm and cytonucleus.</p><p><strong>Conclusion: </strong>The findings of this study suggest a strong correlation between the expression of nuclear factor kappa B in cancer cells and the metastasis of cancer.</p>","PeriodicalId":13173,"journal":{"name":"Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao","volume":"33 1","pages":"23-4, 27"},"PeriodicalIF":0.0000,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The expression of nuclear factor kappa B in cancer cells of human adenocarcinoma].\",\"authors\":\"Yao Chen, Ruixiang Li\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Nuclear factor kappa B is very important in cis-activation which regulates the expression of many genes. This study inquired into the mechanism of cancer cell metastasis.</p><p><strong>Methods: </strong>Immunohistochemical method was used for studying the expression of nuclear factor kappa B in cancer cells of human metastasized rectum adenocarcinoma.</p><p><strong>Results: </strong>Expressed nuclear factor kappa Bp65 was found in the cancer cells of peritumoral tissues and metastasized lymph nodes. The reaction product was located in the cytoplasm and cytonucleus.</p><p><strong>Conclusion: </strong>The findings of this study suggest a strong correlation between the expression of nuclear factor kappa B in cancer cells and the metastasis of cancer.</p>\",\"PeriodicalId\":13173,\"journal\":{\"name\":\"Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao\",\"volume\":\"33 1\",\"pages\":\"23-4, 27\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2002-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[The expression of nuclear factor kappa B in cancer cells of human adenocarcinoma].
Objective: Nuclear factor kappa B is very important in cis-activation which regulates the expression of many genes. This study inquired into the mechanism of cancer cell metastasis.
Methods: Immunohistochemical method was used for studying the expression of nuclear factor kappa B in cancer cells of human metastasized rectum adenocarcinoma.
Results: Expressed nuclear factor kappa Bp65 was found in the cancer cells of peritumoral tissues and metastasized lymph nodes. The reaction product was located in the cytoplasm and cytonucleus.
Conclusion: The findings of this study suggest a strong correlation between the expression of nuclear factor kappa B in cancer cells and the metastasis of cancer.