{"title":"新型抗结核药物脂酶的药理研究进展","authors":"Mahmoud Kamal Muftic","doi":"10.1016/S0366-0869(58)80007-6","DOIUrl":null,"url":null,"abstract":"<div><p>Although several enzymes have previously been tried therapeutically, cerase is the first to show definite antibacterial effect. Low toxicity and highly specific antibacterial activity facilitate clinical research, and the apparent anti-tuberculous activity in both animal and human cases justifies larger scale clinical trials, which are in progress. Besides bibliographical data, this article contains information about the pharmacological properties of cerase, and preliminary observations on its use in the treatment of human tuberculosis.</p></div>","PeriodicalId":100202,"journal":{"name":"British Journal of Tuberculosis and Diseases of the Chest","volume":"52 4","pages":"Pages 308-312"},"PeriodicalIF":0.0000,"publicationDate":"1958-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0366-0869(58)80007-6","citationCount":"1","resultStr":"{\"title\":\"Advances in the pharmacological study of cerase—A new anti-tuberculous agent\",\"authors\":\"Mahmoud Kamal Muftic\",\"doi\":\"10.1016/S0366-0869(58)80007-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Although several enzymes have previously been tried therapeutically, cerase is the first to show definite antibacterial effect. Low toxicity and highly specific antibacterial activity facilitate clinical research, and the apparent anti-tuberculous activity in both animal and human cases justifies larger scale clinical trials, which are in progress. Besides bibliographical data, this article contains information about the pharmacological properties of cerase, and preliminary observations on its use in the treatment of human tuberculosis.</p></div>\",\"PeriodicalId\":100202,\"journal\":{\"name\":\"British Journal of Tuberculosis and Diseases of the Chest\",\"volume\":\"52 4\",\"pages\":\"Pages 308-312\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1958-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0366-0869(58)80007-6\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"British Journal of Tuberculosis and Diseases of the Chest\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0366086958800076\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"British Journal of Tuberculosis and Diseases of the Chest","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0366086958800076","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Advances in the pharmacological study of cerase—A new anti-tuberculous agent
Although several enzymes have previously been tried therapeutically, cerase is the first to show definite antibacterial effect. Low toxicity and highly specific antibacterial activity facilitate clinical research, and the apparent anti-tuberculous activity in both animal and human cases justifies larger scale clinical trials, which are in progress. Besides bibliographical data, this article contains information about the pharmacological properties of cerase, and preliminary observations on its use in the treatment of human tuberculosis.
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