全身给予血红素对大鼠肝脏色氨酸吡咯酶活性的影响

Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects Pub Date : 1964-10-23 DOI:10.1016/0926-6569(64)90267-6

M.V. Jago, J.F. Nelson, S. Rose

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引用次数: 7

摘要

静脉给予血红素溶液后，大鼠肝脏色氨酸吡啶酶的辅因子饱和度明显升高。每100克体重给予0.5-1 μ摩尔或更大剂量的血红素后，血液完全饱和。色氨酸吡啶酶活性在体内没有明显的增加，伴随或跟随这种酶与辅因子的明显饱和。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The effect of systemic administration of haematin on the tryptophan pyrrolase activity of rat liver

The saturation with cofactor of the tryptophan pyrrolase of rat liver was markedly increased by intravenous administration of solutions of haematin. Complete saturation followed the administration of 0.5–1 μmole haematin per 100 g body weight or larger amounts. No significant increase in tryptophan pyrrolase activity accompanied or followed this apparent saturation of the enzyme with cofactor in vivo.

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