{"title":"尿尿酸在体外和体内的光二聚化","authors":"J.H. Anglin Jr., Mark Allen Everett","doi":"10.1016/0926-6577(64)90092-0","DOIUrl":null,"url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. Irradition of urocanic acid or urocanate frozen in aqueous solution with 280–320-mμ light produced a photodimer which was isolated by gradient elution from an anion-exchange resin.</p></span></li><li><span>2.</span><span><p>2. A similar substance was shown to be present in dilute acid extracts of guinea-pig epidermis after irradiation with 280–320-mμ light.</p></span></li><li><span>3.</span><span><p>3. The photodimer formed with 280–320-mμ light when irradiated in solution with 254-mμ light was converted to urocanic acid and smaller amounts of several other products.</p></span></li><li><span>4.</span><span><p>4. Irradiation of crystalline urocanic acid or its solutions does not produce an accumulation of the photodimer.</p></span></li></ul></div>","PeriodicalId":100169,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Biophysical Subjects","volume":"88 3","pages":"Pages 492-501"},"PeriodicalIF":0.0000,"publicationDate":"1964-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6577(64)90092-0","citationCount":"11","resultStr":"{\"title\":\"Photodimerization of urocanic acid in vitro and in vivo\",\"authors\":\"J.H. Anglin Jr., Mark Allen Everett\",\"doi\":\"10.1016/0926-6577(64)90092-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p></p><ul><li><span>1.</span><span><p>1. Irradition of urocanic acid or urocanate frozen in aqueous solution with 280–320-mμ light produced a photodimer which was isolated by gradient elution from an anion-exchange resin.</p></span></li><li><span>2.</span><span><p>2. A similar substance was shown to be present in dilute acid extracts of guinea-pig epidermis after irradiation with 280–320-mμ light.</p></span></li><li><span>3.</span><span><p>3. The photodimer formed with 280–320-mμ light when irradiated in solution with 254-mμ light was converted to urocanic acid and smaller amounts of several other products.</p></span></li><li><span>4.</span><span><p>4. Irradiation of crystalline urocanic acid or its solutions does not produce an accumulation of the photodimer.</p></span></li></ul></div>\",\"PeriodicalId\":100169,\"journal\":{\"name\":\"Biochimica et Biophysica Acta (BBA) - Specialized Section on Biophysical Subjects\",\"volume\":\"88 3\",\"pages\":\"Pages 492-501\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1964-11-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0926-6577(64)90092-0\",\"citationCount\":\"11\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biochimica et Biophysica Acta (BBA) - Specialized Section on Biophysical Subjects\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0926657764900920\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Biophysical Subjects","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0926657764900920","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Photodimerization of urocanic acid in vitro and in vivo
1.
1. Irradition of urocanic acid or urocanate frozen in aqueous solution with 280–320-mμ light produced a photodimer which was isolated by gradient elution from an anion-exchange resin.
2.
2. A similar substance was shown to be present in dilute acid extracts of guinea-pig epidermis after irradiation with 280–320-mμ light.
3.
3. The photodimer formed with 280–320-mμ light when irradiated in solution with 254-mμ light was converted to urocanic acid and smaller amounts of several other products.
4.
4. Irradiation of crystalline urocanic acid or its solutions does not produce an accumulation of the photodimer.