头颈部放疗患者唾液流量的评价。

Q2 Dentistry Pesquisa odontologica brasileira = Brazilian oral research Pub Date : 2003-04-01 Epub Date: 2003-10-10 DOI:10.1590/s1517-74912003000200011

Paulo Rogério Ferreti Bonan, Fábio Ramoa Pires, Márcio Ajudarte Lopes, Osvaldo Di Hipólito

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引用次数: 25

摘要

放疗常用于头颈部鳞状细胞癌的治疗。在副作用中，口干是最重要的副作用之一。为了评估放射治疗对唾液流动的作用，我们进行了三次唾液样本采集:放射治疗开始时、放射治疗期间和放射治疗后。结果表明，第一次采集的唾液流量值与对照组非常相似。然而，在治疗过程中，唾液流量明显减少(p = 0.0008)，放疗后立即继续降低(p = 0.0009)。我们的研究表明放射治疗导致放射治疗期间和之后唾液流量的重要减少。

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Evaluation of salivary flow in patients during head and neck radiotherapy.

Radiotherapy is frequently employed for the treatment of head and neck squamous cell carcinoma. Among the side effects, xerostomia is one of the most important. With the objective of evaluating the role of radiotherapy in salivary flow, we performed three salivary sample collections: at the beginning of, during, and immediately after radiotherapy. The results showed that the salivary flow values of the first collection were very similar to those of the control group. However, during treatment, there was a significant decrease of the salivary flow (p = 0.0008), which continued low immediately after radiotherapy (p = 0.0009). Our study showed that radiotherapy leads to an important reduction of salivary flow during and after radiotherapy.

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来源期刊

Pesquisa odontologica brasileira = Brazilian oral research Dentistry-Dentistry (all)

CiteScore

3.80

自引率

0.00%

发文量

期刊介绍： Pesquisa Odontológica Brasileira is a new quarterly published journal (January-March, April-June, July-September, October-December), with an annual supplement (Anais da Reunião de Pesquisa Odontológica da SBPqO), by the Sociedade Brasileira de Pesquisa Odontológica [Brazilian Society of Odontological Research] and University of São Paulo. It replaces Revista de Odontologia da Universidade de São Paulo (ISSN 0103-0663).