胰岛素治疗可能与COVID-19合并糖尿病患者死亡率增加无关

IF 1.5 4区医学 Q4 ENDOCRINOLOGY & METABOLISM Endocrine Research Pub Date : 2021-02-01 Epub Date: 2021-02-26 DOI:10.1080/07435800.2021.1892748

Chia Siang Kow, Syed Shahzad Hasan

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引用次数: 3

摘要

先前的研究报告称，2019年冠状病毒病(COVID-19)合并糖尿病患者的入院前胰岛素治疗与死亡率显着增加相关。然而，胰岛素使用者和非胰岛素使用者之间血糖控制的基线差异可能会改变这种关联。对胰岛素治疗与死亡率之间关系的误解可能导致临床实践中的混淆，并且可能会在适当指示胰岛素治疗的COVID-19住院患者中省略这种治疗。然而，因COVID-19住院期间对胰岛素的需求可能是预后不良的标志，因此可用于确定需要更积极治疗以预防死亡的患者群体。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Insulin Treatment May Not Be Associated with Increased Mortality in Patients with COVID-19 and Concurrent Diabetes.

Previous study reported that preadmission insulin treatment in patients with coronavirus disease 2019 (COVID-19) and concurrent diabetes was associated with a significantly increased odds of mortality. However, such association may be modified by possible baseline differences in glycemic control between insulin users and non-insulin users. Misinterpretation of the association between insulin treatment and mortality could lead to confusion in clinical practice and hospitalized patients with COVID-19 for whom insulin treatment is appropriately indicated may be omitted from such treatment. However, requirement for insulin during hospitalization for COVID-19 may be a marker of poor prognosis and as such could be used to identify patient population who require more aggressive treatments to prevent mortality.

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来源期刊

Endocrine Research 医学-内分泌学与代谢

CiteScore

4.30

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： This journal publishes original articles relating to endocrinology in the broadest context. Subjects of interest include: receptors and mechanism of action of hormones, methodological advances in the detection and measurement of hormones; structure and chemical properties of hormones. Invitations to submit Brief Reviews are issued to specific authors by the Editors.

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