自身免疫性疾病中的先天淋巴样细胞亚群及其细胞因子。

IF 2.2 4区医学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY European cytokine network Pub Date : 2020-12-01 DOI:10.1684/ecn.2020.0460

Asma Maleki, Jamal Motallebzadeh Khanmiri, Mohammad Khani Eshrat Abadi, Faezeh Soveyzi, Bobak Moazzami, Michael R Hamblin, Nima Rezaei

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引用次数: 2

摘要

免疫系统的先天臂和适应性臂都参与自身免疫性疾病的发展。疾病的主要机制是由于适应性免疫细胞对自身抗原具有活性。这些细胞会对身体组织造成严重损害。先天淋巴样细胞(Innate lymphoid cells, ILCs)是一种重要的先天免疫细胞，近年来其作用越来越受到重视。在自身免疫性疾病的发病机制中，ilc与一些炎症有关。在这篇综述中，我们讨论了白细胞介素在免疫反应中的作用，以及它们在各种自身免疫性疾病中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Innate lymphoid cell subsets and their cytokines in autoimmune diseases.

Both the innate and adaptive arms of the immune system are involved in the development of autoimmune diseases. The main mechanism of disease is due to adaptive immune cells that are active against self-antigens. These cells can cause major damage to body tissues. Innate lymphoid cells (ILCs) are an important type of innate immune cell, whose role has been highlighted in recent years. ILCs are responsible for some of the inflammation in the pathogenesis of autoimmune diseases. In this review, we discuss the role of ILCs in the immune response, as well as their involvement in various autoimmune diseases.

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来源期刊

European cytokine network 生物-免疫学

CiteScore

5.70

自引率

0.00%

发文量

审稿时长

6 months

期刊介绍： The journal that brings together all areas of work involving cytokines. European Cytokine Network is an electronic journal that publishes original articles and abstracts every quarter to provide an essential bridge between researchers and clinicians with an interest in this cutting-edge field. The journal has become a must-read for specialists in the field thanks to its swift publication and international circulation. The journal is referenced in several databases, including Medline, which is testament to its scientific quality.