日本经支气管冷冻活组织检查治疗间质性肺病的可行性、实用性和安全性。

IF 2.3 Multidisciplinary Respiratory Medicine Pub Date : 2021-01-25 eCollection Date: 2021-01-15 DOI:10.4081/mrm.2021.731

Takato Ikeda, Akira Nakao, Fumiyasu Igata, Yoshiaki Kinoshita, Hisako Kushima, Takemasa Matsumoto, Hiroshi Ishii, Kazuki Nabeshima, Masaki Fujita

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引用次数: 0

摘要

背景：经支气管肺冷冻活检术（TBLC）是一种新技术，与传统的经支气管肺活检术相比，它能采集到更多的组织。经支气管肺冷冻活检术正在全球范围内流行，可用于弥漫性肺部疾病和肺癌的治疗。然而，日本仅发表了几篇关于 TBLC 的报道。本研究旨在评估我院 TBLC 的疗效和安全性，并将这些结果与过去的报告进行比较：从 2018 年 4 月至 2020 年 1 月，对在我院接受 TBLC 治疗的 38 例弥漫性肺部疾病患者的年龄、性别、活检部位、活检大小、诊断疾病和并发症进行了评估：接受 TBLC 检查的患者中，男性 20 人，女性 18 人，平均年龄 63.7 岁。平均样本大小为 5.7 毫米，诊断率为 65.7%（25/38）。≥2级并发症包括出血（15.8%）、气胸（2.6%）和心房颤动（2.6%）：结论：TBLC被认为有助于诊断弥漫性肺部疾病，而且可以安全进行。

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Feasibility, utility, and safety of transbronchial cryobiopsy for interstitial lung diseases in Japan.

Background: Transbronchial lung cryobiopsy (TBLC) is a new technique that enables larger tissue collection than can be obtained by conventional transbronchial lung biopsy. TBLC is becoming popular worldwide and is performed for diffuse lung disease and lung cancer. However, only a few reports of TBLC have been published in Japan. This study was performed to evaluate the efficacy and safety of TBLC at our hospital and compare these findings with past reports.

Methods: From April 2018 to January 2020, 38 patients who underwent TBLC for diffuse lung disease at our hospital were evaluated with respect to age, sex, biopsy site, biopsy size, diagnostic disease, and complications.

Results: The patients who underwent TBLC were 20 men and 18 women with an average age of 63.7 years. The average sample size was 5.7 mm, and the diagnostic rate was 65.7% (25/38). Grade ≥2 complications included bleeding (15.8%), pneumothorax (2.6%), and atrial fibrillation (2.6%).

Conclusions: TBLC was considered to be useful for the diagnosis of diffuse lung disease and could be safely performed.

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来源期刊

Multidisciplinary Respiratory Medicine Medicine-Pulmonary and Respiratory Medicine

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期刊介绍： Multidisciplinary Respiratory Medicine is the official journal of the Italian Respiratory Society - Società Italiana di Pneumologia (IRS/SIP). The journal publishes on all aspects of respiratory medicine and related fields, with a particular focus on interdisciplinary and translational research. The interdisciplinary nature of the journal provides a unique opportunity for researchers, clinicians and healthcare professionals across specialties to collaborate and exchange information. The journal provides a high visibility platform for the publication and dissemination of top quality original scientific articles, reviews and important position papers documenting clinical and experimental advances.