[低钾血症和甲状腺毒性麻痹——异同]。

Katarzyna Ziora
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引用次数: 0

摘要

低钾血症性周期性麻痹(HPP)是一种罕见的常染色体显性遗传型肌病,其特征是由于离子通道功能障碍导致血清钾浓度下降而引起间歇性肌无力发作。甲状腺毒性低钾血症性麻痹(TPP)是一种与甲亢直接相关的周期性麻痹的获得性形式。HPP在白种人中占主导地位,而TPP在13-24%的亚洲甲状腺功能亢进患者中发生。两种类型的低钾血症性麻痹的症状相似,即肢体麻痹的突然发作,通常发生在早晨,在夜间休息后,在剧烈运动试验或艰苦工作之前。TPP的治疗和预防与HPP不同。本报告描述了HPP和TPP之间的异同。
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[Hypokalemic and thyrotoxic paralysis--similarities and differences].

Hypokalaemic periodic paralysis (HPP) is a rare myopathy inherited in autosomal dominantly pattern, characterized by episodic attacks of muscle weakness due to the decrease in serum potassium concentration because of ion channel's dysfunction. The thyrotoxic hypokalaemic paralysis (TPP) is an acquired form of a periodic paralysis associated directly with hyperthyroidism. HPP predominates in Caucasians, in contrast to TPP which occurs in 13-24% Asian with hyperthyroidism. Both types of hypokalaemic paralysis are similar in symptoms i.e. the sudden onset of limbs paralysis, often in the morning, after the night rest, preceded by intense exercise testing or hard work. The treatment and the prevention of TPP differs from that of HPP. Both, similarities and differences, between HPP and TPP are described in this report.

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