晚期结直肠癌的医学治疗进展。

V Sultan-Amar, E Fabre-Guillevin, P Piedbois
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引用次数: 0

摘要

在过去的二十年中,晚期结直肠癌(ACC)患者的治疗取得了重大进展。用亚叶酸(LV)调节5-氟尿嘧啶(5-FU),随后引入伊立替康和奥沙利铂,显著改善了这些患者的预后。新的策略包括口服氟嘧啶和靶向药物来抑制癌症信号。
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Progresses in the medical treatment of advanced colorectal cancer.

In the last 2 decades, major progresses have been made in the management of patients with advanced colorectal cancer (ACC). The modulation of 5-fluorouracil (5-FU) by folinic acid (LV), followed by the introduction of irinotecan and oxaliplatin have significantly improved the outcome of these patients. New strategies consist of oral fluoropyrimidines, and of targeted agents to inhibit cancer signalisation.

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