开发非洲人类锥虫病新诊断检测的新举措。

Dietmar Steverding
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引用次数: 18

摘要

非洲人类锥虫病对生活在撒哈拉以南国家的数百万人构成威胁,除非得到治疗,否则会致命。目前用于昏睡病诊断的血清学和寄生虫学检测方法特异性和敏感性较低。显然,迫切需要准确的诊断工具和疾病分期。创新诊断方法基金会和世界卫生组织宣布,它们将合作开发和评估非洲人类锥虫病的新诊断检测方法。
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A new initiative for the development of new diagnostic tests for human African trypanosomiasis.

Human African trypanosomiasis is a threat to millions of people living in sub-Saharan countries and is fatal unless treated. At present, the serological and parasitological tests used in the field for diagnosis of sleeping sickness have low specificity and sensitivity. There is clearly an urgent need for accurate tools for both diagnosis and staging of the disease. The Foundation for Innovative New Diagnostics and the World Health Organization have announced that they will collaborate to develop and evaluate new diagnostic tests for human African trypanosomiasis.

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Consultation meeting on the development of therapeutic vaccines for post kala azar dermal leishmaniasis. In silico, biologically-inspired modelling of genomic variation generation in surface proteins of Trypanosoma cruzi. Genetic diversity of Leishmania amazonensis strains isolated in northeastern Brazil as revealed by DNA sequencing, PCR-based analyses and molecular karyotyping. Dynamics of infection and competition between two strains of Trypanosoma brucei brucei in the tsetse fly observed using fluorescent markers. Consultative meeting to develop a strategy for treatment of cutaneous leishmaniasis. Institute Pasteur, Paris. 13-15 June, 2006.
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