{"title":"[唾液腺肿瘤的DNA倍性和增殖活性]。","authors":"Oliver Driemel, Klaus Kraft, Jörg Hemmer","doi":"10.1007/s10006-007-0060-x","DOIUrl":null,"url":null,"abstract":"<p><p>DNA ploidy and S-Phase fraction (SPF) of 279 salivary gland tumours were analysed using high-resolution DNA flow cytometry. All 229 benign neoplasms were diploid while 12 of 50 malignant tumours showed cell populations with aneuploid DNA content. The SPF values of diploid malignancies were significantly higher if compared with pleomorphic adenomas but did not differ from that of the zystadenolymphoma (Warthin tumour) group. While aneuploidy represents a distinct indicator of malignancy SPF values are of minor relevance for dignity assessment in salivary gland tumours.</p>","PeriodicalId":79515,"journal":{"name":"Mund-, Kiefer- und Gesichtschirurgie : MKG","volume":"11 3","pages":"139-44"},"PeriodicalIF":0.0000,"publicationDate":"2007-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-007-0060-x","citationCount":"1","resultStr":"{\"title\":\"[DNA ploidy and proliferative activity in salivary gland tumours].\",\"authors\":\"Oliver Driemel, Klaus Kraft, Jörg Hemmer\",\"doi\":\"10.1007/s10006-007-0060-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>DNA ploidy and S-Phase fraction (SPF) of 279 salivary gland tumours were analysed using high-resolution DNA flow cytometry. All 229 benign neoplasms were diploid while 12 of 50 malignant tumours showed cell populations with aneuploid DNA content. The SPF values of diploid malignancies were significantly higher if compared with pleomorphic adenomas but did not differ from that of the zystadenolymphoma (Warthin tumour) group. While aneuploidy represents a distinct indicator of malignancy SPF values are of minor relevance for dignity assessment in salivary gland tumours.</p>\",\"PeriodicalId\":79515,\"journal\":{\"name\":\"Mund-, Kiefer- und Gesichtschirurgie : MKG\",\"volume\":\"11 3\",\"pages\":\"139-44\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2007-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1007/s10006-007-0060-x\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Mund-, Kiefer- und Gesichtschirurgie : MKG\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s10006-007-0060-x\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mund-, Kiefer- und Gesichtschirurgie : MKG","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s10006-007-0060-x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[DNA ploidy and proliferative activity in salivary gland tumours].
DNA ploidy and S-Phase fraction (SPF) of 279 salivary gland tumours were analysed using high-resolution DNA flow cytometry. All 229 benign neoplasms were diploid while 12 of 50 malignant tumours showed cell populations with aneuploid DNA content. The SPF values of diploid malignancies were significantly higher if compared with pleomorphic adenomas but did not differ from that of the zystadenolymphoma (Warthin tumour) group. While aneuploidy represents a distinct indicator of malignancy SPF values are of minor relevance for dignity assessment in salivary gland tumours.
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