中国成年男性器官和组织中的元素含量。

Hong-Da Zhu, Jing-Yu Wang, Quan Wu, Nei-Fen Wang, Ti-Jiang Fan, Hu-Sheng Liu, Qing-Fen Liu, Xiao-Yan Wang, Li Ou-Yang, Ya-Qiong Liu, Qing Xie
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引用次数: 0

摘要

目的:为《中国参考人》的相关参数提供参考依据。方法:从河北、山西、江苏、四川4个饮食模式不同的地区对16例刚刚遭遇猝死的健康成年男性进行尸检,获得肌肉、肋骨、肝脏等18种主要器官或组织标本。同时,研究人员从生活在这些地区的10名志愿者身上采集了全血样本。采用电感耦合等离子体质谱法(ICP-MS)、电感耦合等离子体原子发射光谱法(ICP-AES)和石墨炉原子吸收光谱法(GF-AAS)检测样品中56种元素的浓度。根据获得的这些器官或组织重量的浓度和参考值,估计这些器官或组织以及整个身体的相对元素负担。结果:共测定了18个主要脏器或组织中56种元素的浓度,并估计了其元素脏器或组织及全身负荷。此外,重点讨论了辐射防护的重要元素在这些器官或组织中的分布。结论:通过与以往相关结果的汇总,本系列研究的总体结果可以为中国参考人提供比以往更可靠、更具代表性的参考值依据。
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Elemental contents in organs and tissues of Chinese adult men.

Objective: To provide basis of reference values for relevant parameters of Chinese Reference Man.

Methods: Eighteen kinds of major organ or tissue samples, including muscle, rib, liver, and so on, were obtained from 4 areas (Hebei, Shanxi, Jiangsu, and Sichuan provinces) with different dietary patterns in China in autopsy of 16 healthy adult men, who had just encountered sudden deaths. At the same time, whole blood samples were collected from 10 volunteers living in each of these areas. The concentrations of 56 elements in these samples were detected by using Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Inductively Coupled Plasma Atomic Emission Spectrometry (ICP-AES), and Graphite Furnace Atomic Absorption Spectrometry (GF-AAS) techniques. Based on obtained concentrations and reference values of these organ or tissue weights for Chinese Reference Man, the relative elemental burdens in these organs or tissues as well whole body were also estimated.

Results: The concentrations of 56 elements in 18 main organs or tissues were determined all together and their elemental organ or tissue and whole body burdens were estimated. Furthermore, the distributions of important elements for radiation protection in these organs or tissues were emphatically discussed.

Conclusion: By summing with past related results, the total results obtained from the series of research may provide more reliable and better representative basis of these reference values for Chinese Reference Man than before.

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