Abdalla Shalaby Prof., Maha El-Tohamy, Magda El-Maamly, Hassan Y. Aboul-Enein Prof.
{"title":"选择性测定药物制剂和生物液体中哌替啶的电位膜传感器","authors":"Abdalla Shalaby Prof., Maha El-Tohamy, Magda El-Maamly, Hassan Y. Aboul-Enein Prof.","doi":"10.1002/adic.200790090","DOIUrl":null,"url":null,"abstract":"<p>The construction and general performance characteristics of a novel potentiometric PVC membrane sensor based on pethidine-phosphomolybdate as electroactive material for the determination of pethidine are described. This sensor exhibits fast, stable and near-Nernstain response 55.24±0.1, over the concentration range 1.10<sup>-2</sup>-1.10<sup>-5</sup>M for pethidine-phosphomolybdate over pH 2-7. No interferences are caused by many organic, inorganic cations, alkaloids and amino acids. The sensor proved useful for determining pethidine in pure forms, pharmaceutical injections and monitoring the content uniformity assay of ampoules. The designed sensor also show good accuracy for the determination of pethidine in biological fluids.</p>","PeriodicalId":8193,"journal":{"name":"Annali di chimica","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2007-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/adic.200790090","citationCount":"8","resultStr":"{\"title\":\"Potentiometric Membrane Sensor for the Selective Determination of Pethidine in Pharmaceutical Preparations and Biological Fluids\",\"authors\":\"Abdalla Shalaby Prof., Maha El-Tohamy, Magda El-Maamly, Hassan Y. Aboul-Enein Prof.\",\"doi\":\"10.1002/adic.200790090\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The construction and general performance characteristics of a novel potentiometric PVC membrane sensor based on pethidine-phosphomolybdate as electroactive material for the determination of pethidine are described. This sensor exhibits fast, stable and near-Nernstain response 55.24±0.1, over the concentration range 1.10<sup>-2</sup>-1.10<sup>-5</sup>M for pethidine-phosphomolybdate over pH 2-7. No interferences are caused by many organic, inorganic cations, alkaloids and amino acids. The sensor proved useful for determining pethidine in pure forms, pharmaceutical injections and monitoring the content uniformity assay of ampoules. The designed sensor also show good accuracy for the determination of pethidine in biological fluids.</p>\",\"PeriodicalId\":8193,\"journal\":{\"name\":\"Annali di chimica\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2007-09-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1002/adic.200790090\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annali di chimica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/adic.200790090\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annali di chimica","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/adic.200790090","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Potentiometric Membrane Sensor for the Selective Determination of Pethidine in Pharmaceutical Preparations and Biological Fluids
The construction and general performance characteristics of a novel potentiometric PVC membrane sensor based on pethidine-phosphomolybdate as electroactive material for the determination of pethidine are described. This sensor exhibits fast, stable and near-Nernstain response 55.24±0.1, over the concentration range 1.10-2-1.10-5M for pethidine-phosphomolybdate over pH 2-7. No interferences are caused by many organic, inorganic cations, alkaloids and amino acids. The sensor proved useful for determining pethidine in pure forms, pharmaceutical injections and monitoring the content uniformity assay of ampoules. The designed sensor also show good accuracy for the determination of pethidine in biological fluids.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
