民间医药中一些植物提取物的抗菌活性。

Rathish Nair, Tamanna Kalariya, Sumitra Chanda
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引用次数: 51

摘要

在本工作中,筛选了一些具有潜在抗菌活性的植物。用甲醇水溶液和有机溶剂进行抑菌活性评价。筛选的植物有:蜜树、麻疯树、白花树、印楝、金牛花和板栗。对睾酮假单胞菌、表皮葡萄球菌、肺炎克雷伯菌、枯草芽孢杆菌、莫氏变形杆菌、黄微球菌等6种细菌进行抑菌活性评价。采用琼脂盘扩散法和琼脂沟扩散法对这些植物的抗菌活性进行了研究。睾酮链球菌和肺炎克雷伯菌是最耐药的菌株。A. indica对被试菌株表现出较强的抑菌活性。因此,我们认为籼稻可能是一种有前景的药物,应进一步探索该化合物以确定其全部治疗潜力。此外,其叶提取物还可以作为抗所研究菌株引起的疾病的先导分子。
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Antibacterial activity of some plant extracts used in folk medicine.

In the present work, selected plants were screened for their potential antibacterial activity. For evaluating antibacterial activity, both aqueous and organic solvent methanol was used. The plants screened were Ocimum sanctum, Jatropha gossypifolia, Boerhavia diffusa, Azadirachta indica, Solidago virgaurea, and Commelina benghalensis. The antibacterial activity was assessed against six bacterial strains--Pseudomonas testosteroni, Staphylococcus epidermidis, Klebsiella pneumoniae, Bacillus subtilis, Proteus morganii, Micrococcus flavus. Agar disc diffusion method and Agar ditch diffusion method were used to study the antibacterial activity of all these plants. Ps. testosteroni and K. pneumoniae were the most resistant bacterial strains. A. indica showed strong activity against tested bacterial strains. Therefore, we conclude that A. indica may prove to be a promising agent, and further exploration into this compound should be performed to determine its full therapeutic potential. In addition, its leaf extract can also be used as a lead molecule in combating the diseases caused by the studied bacterial strains.

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