库欣反应对全身动脉压的影响。

IEEE Engineering in Medicine and Biology Magazine Pub Date : 2009-11-01 DOI:10.1109/MEMB.2009.934622

Mauro Ursino, Massimo Giannessi, Marta Frapparelli, Elisa Magosso

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引用次数: 9

摘要

本研究通过一个原始的数学模型探讨了脑血管动力学、颅内压(ICP)、库欣反应和短期系统调节之间的复杂关系。该模型用于分析库欣响应在ICP持续升高和ICP平台波发生期间对心脑血管数量的影响，并研究导致系统不稳定的条件，形成缓慢(0.05-0.1 Hz)动脉压力波。该模型可能有助于临床医生在库欣反应的临床益处和缺点之间找到平衡。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Effect of cushing response on systemic arterial pressure.

This work investigates the complex relationships between cerebrovascular dynamics, intracranial pressure (ICP), Cushing response, and short-term systemic regulation via an original mathematical model. The model has been used to analyze the effects of Cushing response on cardiovascular and cerebrovascular quantities during constant ICP elevation and during the occurrence of ICP plateau waves and to investigate the conditions leading to system instability with the formation of slow (0.05-0.1 Hz) arterial pressure waves. The model may be of value to assist clinicians in finding the balance between clinical benefits of Cushing response and its shortcomings.

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