[中国后根除时代使用Sabin-IPV免疫的可行性研究]

中国疫苗和免疫 Pub Date : 2010-02-01
Yan-Chun Che, Li Jiang, Cong-Wen Shao
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引用次数: 0

摘要

根据世界卫生组织(世卫组织)的观点,根除后时代即将到来,其优先事项是全球认证根除野生脊髓灰质炎病毒,届时将停止使用口服脊髓灰质炎减毒活疫苗(OPV),同步使用灭活脊髓灰质炎病毒疫苗(IPV),特别是建议在发展中国家持续使用价格合理的Sabin-IPV (sIPV),直到最终根除脊髓灰质炎。然而,国际上还没有成功研制出sIPV。本文对工业发达国家sIPV免疫策略、发展现状及使用情况进行了初步分析。分析了sIPV在中国潜在使用的可行性,包括免疫策略、计划、生产技术和供应能力。中国应加快sIPV的发展,以便为根除后时代的生产技术做好准备。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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[Feasibility study of using Sabin-IPV immunization in post-eradication era in China].

Based upon the World Health Organization (WHO)'s perspective, the post-eradication era is coming with a priority of global certifying the wild poliovirus eradication, by which then the Oral Poliomyelitis Attenuated Live Vaccine (OPV) will be ceased and Inactivated Poliovirus Vaccine (IPV) will be synchronized used, in particular the affordable Sabin-IPV (sIPV) is recommended to be used continuously in developing countries till the final eradication of poliomyelitis. However, no any sIPV has successfully been developed in the world. In this paper, the sIPV immunization strategy, current development status and its usage in industrialized countries are preliminarily analyzed. Feasibility analysis of potential sIPV usage in China, including immunization strategy, schedule, production technology and supply capacity is analysed as well. sIPV development in China should be accelerated in order to prepare production technology to the post-eradication era.

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