睾丸腺瘤样肿瘤。

Waqas Amin, Anil V Parwani
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引用次数: 33

摘要

腺瘤样肿瘤占所有睾丸旁肿物的30%。这些通常是无症状、生长缓慢的肿块。它们是一种良性肿瘤,由立方体到柱状细胞的索和小管组成,细胞质为液泡状,间质为纤维质。组织化学研究和Wilms肿瘤1基因表达的遗传分析支持它们被认为是间皮起源。切除活检既是诊断又是治疗。临床主要考虑的是准确诊断,防止不必要的睾丸切除术。诊断检查包括血清肿瘤标志物(α胎蛋白、β HCG、LDH阴性)超声检查(低回声和均匀外观)和冷冻切片。
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Adenomatoid tumor of testis.

Adenomatoid tumors are responsible for 30% of all paratesticular masses. These are usually asymptomatic, slow growing masses. They are benign tumors comprising of cords and tubules of cuboidal to columnar cells with vacuolated cytoplasm and fibrous stroma. They are considered to be of mesothelial origin supported by histochemical studies and genetic analysis of Wilms tumor 1 gene expression. Excision biopsy is both diagnostic and therapeutic procedure. The main clinical consideration is accurate diagnosis preventing unnecessary orchiectomy. Diagnostic studies include serum tumor markers (negative alpha fetoprotein, beta HCG, LDH) ultrasonography (hypoechoic and homogenous appearance) and frozen section.

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