利妥昔单抗的使用和HBV的再激活。

Hepatitis research and treatment Pub Date : 2010-01-01 Epub Date: 2010-12-01 DOI:10.1155/2010/182067
Yutaka Tsutsumi, Reiki Ogasawara, Yusuke Kamihara, Shinichi Ito, Yoshiya Yamamoto, Junji Tanaka, Masahiro Asaka, Masahiro Imamura
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引用次数: 23

摘要

利妥昔单抗是一种用于治疗b细胞非霍奇金淋巴瘤的药物,其使用范围已扩大到治疗胶原蛋白疾病,如特发性血小板减少性紫癜和类风湿性关节炎。使用利妥昔单抗的一个严重并发症是潜伏的乙型肝炎病毒的再激活,预防这一现象已成为一个紧迫的问题。本文通过对我们和其他小组迄今为止所经历的患者病例的分析,提供了问题的总体轮廓。
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Rituximab administration and reactivation of HBV.

Rituximab is a drug used for the treatment of B-cell non-Hodgkin's lymphoma, and its range of use has expanded to the treatment of collagen diseases such as idiopathic thrombocytopenic purpura and rheumatoid arthritis. One serious complication of rituximab use is the reactivation of dormant hepatitis B virus, and prevention of this phenomenon has become an urgent issue. This paper provides a general outline of the problem through an analysis of patient cases that we and other groups have experienced to date.

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