放疗计划和实施的进展:新的期望,新的护理标准。

Frontiers of Radiation Therapy and Oncology Pub Date : 2011-01-01 Epub Date: 2011-05-20 DOI:10.1159/000322396
James A Purdy
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引用次数: 10

摘要

放射治疗的实践继续建立在治疗计划和输送技术的快速进步之上,这为改善治疗结果带来了真正的潜力。制造商已经采用先进的计算机和成像技术来生产治疗计划/输送系统,这些系统能够精确地形成剂量分布,即使是最复杂的形状也能保形靶体积覆盖,并能保形避免特定的敏感正常结构。然而,这些新系统导致了更复杂、更不直观的计划和治疗交付过程,这给质量保证/治疗验证带来了巨大挑战。计划和交付技术的进步将继续以创纪录的速度发生,推动该领域对放射治疗的准确性、可靠性和适用性产生更高的期望,并引领该领域达到新的护理标准。然而,这种乐观情绪必须与实现这一目标的意识相调和,如果我们要跟上这些快速规划和交付发展的步伐,迫切需要在3个领域取得进展,(1)肿瘤总体积和临床靶体积规格的准确性,(2)放射肿瘤学信息学和(3)质量保证。
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Advances in the planning and delivery of radiotherapy: new expectations, new standards of care.

The practice of radiation therapy continues to build on rapid advancements in treatment planning and delivery technology, which brings real potential for improving treatment outcomes. Manufacturers have employed advanced computer and imaging technology to produce treatment planning/delivery systems capable of precise shaping of dose distributions, conformal target volume coverage for even the most complex shapes and conformal avoidance of specified sensitive normal structures. However, these new systems have led to a more complex, less intuitive planning and treatment delivery process that presents great challenges for quality assurance/treatment verification. Advances in planning and delivery technologies will continue to occur at record paces, pushing the field toward even higher expectations for radiotherapy accuracy, reliability and applicability and leading the field to new standards of care. However, this optimism must be tempered with the realizations that for this to happen, progress is urgently needed in 3 areas, (1) accuracy in specification of gross tumor volume and clinical target volume, (2) radiation oncology informatics and (3) quality assurance, if we are to keep pace with these rapid planning and delivery developments.

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Advances in the planning and delivery of radiotherapy: new expectations, new standards of care. The expanding roles of stereotactic body radiation therapy and oligofractionation: toward a new practice of radiotherapy. Stereotactic body radiation therapy: normal tissue and tumor control effects with large dose per fraction. Stereotactic body radiation therapy for thoracic cancers: recommendations for patient selection, setup and therapy. Stereotactic body radiation therapy for gastrointestinal malignancies.
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