带便携式伽马照相机的变半径针孔SPECT系统的研制

F. Pino , N. Roé , A. Orero , C. Falcón , S. Rojas , J.M. Benlloch , D. Ros , J. Pavía
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引用次数: 18

摘要

目的研制一种配备针孔准直器、连续闪烁晶体和位置敏感光电倍增管的低成本商用便携式伽马照相机,用于小动物SPECT系统。材料和方法伽玛相机连接到一个可变半径系统,这使我们能够通过调整旋转半径来优化灵敏度和分辨率的对象的大小。为了研究SPECT系统对小动物成像的能力,我们评估了分辨率和校准参数对半径的依赖性,并进行了小动物模型和小鼠的采集。结果获得了半径为21.4 mm时1.0 mm和半径为37.2 mm时1.4 mm的分辨率值,从而证明了对变半径SPECT系统的兴趣。结论该系统对小动物和动物的成像质量满意,证实了该系统对小动物SPECT成像的实用性。
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Development of a variable-radius pinhole SPECT system with a portable gamma camera

Objective

To develop a small-animal SPECT system using a low cost commercial portable gamma camera equipped with a pinhole collimator, a continuous scintillation crystal and a position-sensitive photomultiplier tube.

Material and methods

The gamma camera was attached to a variable radius system, which enabled us to optimize sensitivity and resolution by adjusting the radius of rotation to the size of the object. To investigate the capability of the SPECT system for small animal imaging, the dependence of resolution and calibration parameters on radius was assessed and acquisitions of small phantoms and mice were carried out.

Results

Resolution values, ranging from 1.0 mm for a radius of 21.4 mm and 1.4 mm for a radius of 37.2 mm were obtained, thereby justifying the interest of a variable radius SPECT system.

Conclusions

The image quality of phantoms and animals were satisfactory, thus confirming the usefulness of the system for small animal SPECT imaging.

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