全国择期腹疝修补术后住院时间延长和再入院情况分析。

Danish medical bulletin Pub Date : 2011-10-01
Frederik Helgstrand, Jacob Rosenberg, Henrik Kehlet, Thue Bisgaard
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引用次数: 0

摘要

导读:择期腹疝修补术后的早期结果并不令人满意,但缺乏详细的分析。本研究的目的是描述选择性腹疝修补术后延长住院时间(LOS)、再入院和死亡< 30天的病因。材料和方法:本研究是一项全国性的病例对照研究,基于2008年在丹麦进行的选择性腹疝修补术(切口、脐/上腹部、口旁和其他罕见的腹疝修补术)的前瞻性结果。排除标准为急诊手术和腹疝修补术。研究组为预后不良的患者(生存时间≥5天和/或再入院和/或死亡≤30天),对照组为无预后不良的患者。主要并发症被定义为严重和可能致命的并发症。结果:该队列包括2258例患者(研究组258例患者(259例修复),对照组2000例患者(2016例修复))。研究组患者接受切口(76%对28%,p < 0.001)、造口旁(3%对1%,p = 0.001)和复发性疝(21%对12%,p < 0.001)修复的频率明显更高。此外,研究组的疝缺损明显大于对照组(中位数为8 cm vs 2 cm, p < 0.001)。延长的LOS主要是由于疼痛(27%)、主要并发症(19%)和血肿形成(9%)。再入院主要是由于伤口感染和疼痛。结论:腹疝修补术后再入院和延长住院时间的主要原因是疼痛、重大并发症、伤口感染和血肿形成。资助:工程师约翰基金会。E. Ormstrup及其妻子Grete Ormstrup和新西兰地区卫生保健研究基金会为这项研究提供了资金。试验注册:该研究已在丹麦数据保护局注册(参考号:2008-58-0020)及www.clinicaltrials.gov(参考编号:NCT01388634)。
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Nationwide analysis of prolonged hospital stay and readmission after elective ventral hernia repair.

Introduction: Early outcome after elective ventral hernia repair is unsatisfactory, but detailed analyses are lacking. The aim of this study was to describe the aetiology of prolonged hospital stay (LOS), readmission and death < 30 days after elective ventral hernia repair.

Material and methods: The present study was a nationwide case-control study based on prospective results from elective ventral hernia repairs (incisional, umbilical/epigastric, parastomal and other rare ventral hernia repairs) performed in Denmark during 2008. The exclusion criteria were emergency operation and ventral hernia repair in addition to another surgical procedure. The study group were patients with poor outcome (a LOS ≥ 5 days and/or readmission and/or death ≤ 30 days) and the control group were patients without a poor outcome. Major complications were defined as severe and potentially fatal complications.

Results: The cohort included 2,258 patients (a study group counting 258 patients (259 repairs) and a control group comprising 2,000 patients (2,016 repairs)). Patients in the study group underwent repair significantly more often for incisional (76% versus 28%, p < 0.001), parastomal (3% versus 1%, p = 0.001) and recurrent hernia (21% versus 12%, p < 0.001). Furthermore, hernia defects were significantly larger (median 8 cm versus 2 cm, p < 0.001) in the study group than in the control group. Prolonged LOS was mainly due to pain (27%), major complications (19%), and seroma formation (9%). Readmissions were primarily caused by wound infections and pain.

Conclusion: Readmissions and prolonged hospital stay after ventral hernia repair were mainly due to pain, major complications, wound infections and seroma formation.

Funding: The foundation of Engineer Johs. E. Ormstrup and wife Grete Ormstrup and Region Zealand"s foundation for health-care research provided funding for this study.

Trial registration: The study was registered with the Danish Data Protection Agency (ref. no. 2008-58-0020) and www.clinicaltrials.gov (ref. no. NCT01388634).

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Danish medical bulletin
Danish medical bulletin 医学-医学:内科
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