小儿脑神经麻痹。鞍生殖细胞瘤1例报告。

Mbu Kalenga, N Collignon, C Andris, M Deprez, B Otto
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摘要

目的:第三脑神经麻痹在儿童和青少年中并不常见,通常是先天性的。鞍区生殖细胞瘤和眼麻痹的结合在这个年龄被认为是非常罕见的。病例报告:一名11岁的小女孩,因第三左脑神经部分麻痹,并伴有一年的垂体功能低下病史,并伴有平淡的糖尿病和生长迟缓而接受急诊检查。脑IRM显示脑垂体肿瘤。在组织病理学检查的垂体活检,病变是相容的鞍生殖细胞瘤。结论:儿童期第三脑神经麻痹虽然多为先天性,但可能继发于其他原因,应始终牢记。当它们继发于鞍区肿瘤时,根据临床表现和IRM,活检的组织病理学检查是必须的,以获得准确的诊断。
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[Third cranial nerve palsies in childhood. A case report of sellar germ cell tumor].

Purpose: Third cranial nerve palsies are unfrequent in childhood and adolescence and are most often congenital. The association of sellar germ cell tumor and ophthalmoplegia is considered as being very rare at this age.

Case report: A 11-year-old young girl was examined in emergency with a third left cranial nerve partial palsy associated with one- year duration history of hypopituitarism with insipid diabetes and growth retardation. Cerebral IRM revealed a tumor of the pituitary gland. In histopathological examination of pituitary gland biopsies, lesions were compatibles with a sellar germ cell tumor.

Conclusion: Although they are most often of a congenital nature, third cranial nerve palsies in childhood may be secondary to other causes that should be always taken in mind. When they are secondary to a sellar tumor and according to the clinical presentation and the IRM, the histopahological examination of biopsies is mandatory to have a precise diagnosis.

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