IgA多发性骨髓瘤合并月牙状肾小球肾炎1例。

Nephron Extra Pub Date : 2011-01-01 Epub Date: 2011-09-08 DOI:10.1159/000331217

Grace T Moscoso-Solorzano, Marcus V Madureira-Silva, Carlos Balda, Marcello F Franco, Gianna Mastroianni-Kirsztajn

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引用次数: 5

摘要

背景:很少有报告肾小球肾炎(GN)呈新月形，病程迅速进展，可诊断为先前未怀疑的b细胞病变。病例介绍:我们报告一例快速进展的GN:患者在活检时没有显示病因的证据，在肾脏活检的调查中被诊断为IgA多发性骨髓瘤(MM)。肾呈弥漫性增生性、渗出性肾变性，肾浆细胞浸润明显。结论:本病例提示增生性GN伴新月形可能是MM罕见的表现形式。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Crescentic glomerulonephritis in IgA multiple myeloma: a case report.

Background: There are few reports of glomerulonephritis (GN) with crescents and a rapidly progressive course that lead to a diagnosis of a previously unsuspected B-cell dyscrasia.

Case presentation: We report a case of rapidly progressive GN: the patient showed no evidence of etiology at the time of biopsy and was diagnosed as IgA multiple myeloma (MM) during investigation based on a renal biopsy. He presented diffuse proliferative and exudative GN and marked plasma cell infiltration of the kidney.

Conclusion: The present case raises the possibility that proliferative GN with crescents may be a rare mode of presentation of MM.

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来源期刊

Nephron Extra

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： An open-access subjournal to Nephron. ''Nephron EXTRA'' publishes additional high-quality articles that cannot be published in the main journal ''Nephron'' due to space limitations.