青少年原发性高血压诊断试验的应用

Esther Y Yoon, Lisa Cohn, Albert Rocchini, David Kershaw, Gary Freed, Frank Ascione, Sarah Clark
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引用次数: 14

摘要

目的:介绍青少年原发性高血压诊断试验的应用情况。设计:对行政索赔数据进行纵向分析。背景:2003年至2008年期间的密歇根医疗补助计划。参与者:有3年或3年以上医疗补助资格(≥11个月/年)的青少年,诊断为原发性高血压,并有1项或1项以上的抗高血压药物药房索赔。主要结局指标:我们检查了青少年的超声心动图使用情况,并将其与心电图(EKG)和肾超声检查的使用情况进行了比较。我们检查了与第一个药房索赔相关的3种诊断测试的时间。我们检查了患者的人口统计数据和肥胖相关合并症的存在。结果:2003 ~ 2008年,共有951名青少年原发性高血压患者有抗高血压药物索赔;24%(226)有超声心动图;22%(207例)有肾脏超声检查;50%(478例)有心电图。男性(优势比[OR], 1.53;95% CI, 1.06-2.21),更年轻的青少年(OR, 1.69;95% CI, 1.17-2.44),有心电图的患者(OR, 5.79;95% CI, 4.02-8.36)和肾超声检查(OR, 2.22;95% CI, 1.54-3.20)与女性、年龄较大的青少年和未做心电图或肾脏超声检查的青少年相比,更有可能获得超声心动图。结论:指南推荐的诊断检查——超声心动图和肾超声检查——在青少年原发性高血压患者中同样不适用。原发性高血压青少年超声心动图的使用存在性别和年龄差异。决定和选择诊断测试来评估青少年原发性高血压需要进一步研究,以了解这些决定的基本原理并确定治疗效果。
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Use of diagnostic tests in adolescents with essential hypertension.

Objective: To describe the use of diagnostic tests in adolescents with essential hypertension.

Design: Longitudinal analysis of administrative claims data.

Setting: Michigan Medicaid program during 2003 to 2008.

Participants: Adolescents with 3 or more years of Medicaid eligibility (≥ 11 months/y) who had a diagnosis of essential hypertension and 1 or more antihypertensive medication pharmacy claims.

Main outcome measures: We examined adolescents' echocardiogram use and compared it with electrocardiogram (EKG) and renal ultrasonography use. We examined timing of the 3 diagnostic tests in relation to the first pharmacy claim. We examined patient demographics and presence of obesity-related comorbidities.

Results: During 2003 to 2008, there were 951 adolescents with essential hypertension who had antihypertensive pharmacy claims; 24% (226) had echocardiograms; 22% (207) had renal ultrasonography; and 50% (478) had EKGs. Males (odds ratio [OR], 1.53; 95% CI, 1.06-2.21), younger adolescents (OR, 1.69; 95% CI, 1.17-2.44), those who had EKGs (OR, 5.79; 95% CI, 4.02-8.36), and those who had renal ultrasonography (OR, 2.22; 95% CI, 1.54-3.20) were more likely to obtain echocardiograms compared with females, older adolescents, and adolescents who did not have EKGs or renal ultrasonography.

Conclusions: Guideline-recommended diagnostic tests-echocardiograms and renal ultrasonography-were equally poorly used by adolescents with essential hypertension. Sex and age differences exist in the use of echocardiograms by adolescents with essential hypertension. The decision and choice of diagnostic tests to evaluate adolescents with essential hypertension warrant further study to understand the underlying rationale for those decisions and to determine treatment effectiveness.

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