由点突变产生的一个HLA-A空等位基因(A*24:132N),外显子3上有一个停止密码子。

Tissue antigens Pub Date : 2012-11-01 Epub Date: 2012-08-24 DOI:10.1111/j.1399-0039.2012.01949.x
H-Y Zou, S-Z Jin, Z Li
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引用次数: 3

摘要

HLA-A*24:132N的外显子1-8与HLA-A*24:02:01的外显子相同,除了在第3外显子nt 746从C到A有一个核苷酸变化。
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A HLA-A null allele (A*24:132N) with a stop codon in exon 3 generated by a point mutation.

Exons 1-8 of HLA-A*24:132N allele are identical to those of HLA-A*24:02:01:01, except for one nucleotide change at nt 746 in exon 3 from C to A.

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来源期刊
Tissue antigens
Tissue antigens 医学-病理学
自引率
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审稿时长
6 months
期刊最新文献
Identification of a novel HLA-DRB1*14 allele, HLA-DRB1*14:143, by sequence-based typing. Identification of the novel HLA-A allele, HLA-A*24:96, in a Chinese individual. CCR5 gene polymorphism is a genetic risk factor for radiographic severity of rheumatoid arthritis. A HLA-A null allele (A*24:132N) with a stop codon in exon 3 generated by a point mutation. Detection of complement-fixing and non-fixing antibodies specific for endothelial precursor cells and lymphocytes using flow cytometry.
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