小肠结肠炎耶尔森菌的系统发育、致病性和遗传多样性。

Rafał Gierczyński
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引用次数: 0

摘要

在过去的十年中,人们对小肠结肠炎致病性和毒力的研究有了很大的进展。在此期间,观察到高致病性小肠结肠炎菌生物血清型1B/O8的地理分布发生了变化。2003年,美国谱系的主要代表小肠结肠炎杆菌1B/O8在欧洲出现,在波兰流行。主要致病性生物血清型的全基因组已经获得,这在小肠结肠炎菌的基因分型和系统发育方面取得了重大进展。本研究试图将小肠结肠炎致病性和分子流行病学领域的新进展结合起来,以提高人们对该领域的兴趣,并鼓励进一步的研究,以更好地了解波兰耶尔森菌病的流行病学。
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[Phylogeny, pathogenicity and genetic diversity of Yersinia enterocolitica].

The past decade has witnessed a significant expansion of knowledge in field of Y. enterocolitica pathogenicity and virulence. In this period, a change of high-pathogenicity Y. enterocolitica bioserotype 1B/O8 geographical distribution has been observed. In 2003, Y. enterocolitica 1B/O8, major representative ofAmerican lineage, emerged in Europe, where it prevails in Poland. Complete genomes of major pathogenic bioserotypes have been made available, triggering substantial advances in genotyping and phylogeny of Y. enterocolitica. This study attempts to bring together the novelty in field of Y. enterocolitica pathogenicity and molecular epidemiology to rise the interest in the field, and to encourage further studies to better understand epidemiology ofyersiniosis in Poland.

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