关于草药标准化的事实:综述。

Vandana Garg, Vir Ji Dhar, Anupam Sharma, Rohit Dutt
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引用次数: 74

摘要

天然产物,无论是作为纯化合物还是作为标准化的植物提取物,由于化学多样性无与伦比的可用性,为新药先导提供了广泛的机会。与现代药物相比,草药经常用于治疗慢性疾病。标准化保证了一种或多种有效成分和标记化合物的含量。植物环境和遗传因素可以显著影响植物提取物的生化成分,其中植物仍然是最丰富和最具成本效益的药物创新资源。植物性药物的生产需要源植物在完全标准化的条件下进行基因统一的单一栽培,以确保生物化学的一致性,并优化每种作物的安全性和有效性。本文阐述了中药标准化的方法,以及如何制备质量一致、效果一致的中药。
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Facts about standardization of herbal medicine: a review.

Natural products, either as pure compounds or as standardized plant extracts, provide extensive opportunities for new drug leads because of the unmatched availability of chemical diversity. In contrast to modern medicines, herbal medicines are frequently used to treat chronic diseases. Standardization guarantees the content of one or more active constituents and marker compounds. The plant environment and genetic factors could significantly affect the biochemical components of the plant extract, in which plants are still the most abundant and cost-effective resource for drug innovation. Production of botanical drugs requires genetically uniform monocultures of the source plant in fully standardized conditions, to assure the biochemical consistency and to optimize the safety and efficacy of every crop. The present review article illustrates about the methods for standardization of herbal medicine and how the goal of preparing herbal medicines of consistent quality and effects can be achieved.

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