李斯特菌噬菌体:基因组、进化和应用。

Bacteriophage Pub Date : 2013-07-01 Epub Date: 2013-10-24 DOI:10.4161/bact.26861
Jochen Klumpp, Martin J Loessner
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引用次数: 0

摘要

李斯特菌是一种重要的食源性病原体,也是李斯特菌病的病原体,李斯特菌病是一种潜在的致命性感染。在过去的几十年中,已经描述了几百种李斯特菌噬菌体,但只有少数噬菌体的特征得到了详细描述,其中只有不到 20 种噬菌体的基因组序列可供使用。我们在此概述目前已知的李斯特菌噬菌体基因组学、它们在宿主进化和致病性中的作用,以及它们在生物技术和诊断学中的各种应用。
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Listeria phages: Genomes, evolution, and application.

Listeria is an important foodborne pathogen and the causative agent of Listeriosis, a potentially fatal infection. Several hundred Listeria bacteriophages have been described over the past decades, but only few have actually been characterized in some detail, and genome sequences are available for less than twenty of them. We here present an overview of what is currently known about Listeria phage genomics, their role in host evolution and pathogenicity, and their various applications in biotechnology and diagnostics.

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