一名终末期肾衰竭患者的水痘脑炎和肺炎。

Q1 Medicine Asia Pacific Family Medicine Pub Date : 2014-02-21 DOI:10.1186/1447-056X-13-4
Lian Leng Low, Farhad Fakhrudin Vasanwala, Sufi Muhammad Suhail
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引用次数: 0

摘要

我们描述了一名接受血液透析的终末期肾衰竭(ESRF)患者因原发性水痘感染并发水痘肺炎和脑炎而入住我科。水痘感染会导致 ESRF 透析和移植患者的严重发病率和死亡率。迄今公布的证据表明,水痘减毒活疫苗对 ESRF 和肾移植患者有效且安全。世界上已有少数国家制定了针对 ESRF 患者的水痘免疫接种指南。然而,在亚太地区,由于缺乏全国性的共识指南,水痘疫苗尚未得到广泛接种。我们的病例表明,免疫力低下的患者随时都可能发生原发性水痘感染,并因此遭受严重后果。随着慢性肾脏病的负担日益加重,亚太地区的肾脏内科医生和家庭医生应该开会研究每个国家的流行病学数据,并就如何为高危人群接种水痘疫苗制定共识指南。
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Varicella encephalitis and pneumonia in a patient with end stage renal failure.

We describe a patient with end stage renal failure (ESRF) on hemodialysis who was admitted to our department for primary varicella infection complicated by varicella pneumonia and encephalitis. Varicella infections results in serious morbidity and mortality in ESRF dialysis and transplant patients. Evidence published thus far suggests that live attenuated varicella vaccines are effective and safe in ESRF and renal transplant patients. Worldwide a few countries have instituted guidelines for the varicella immunisation in ESRF patients. However, in the Asia Pacific Region, it has not been widely given due to the lack of national consensus guidelines. Our case depicts that primary varicella infection can occur at any time in immunosupressed patients and thus suffer serious consequences from it. With increasing burden of chronic kidney disease, Renal Physicians and Family Physicians in the Asia Pacific Region should meet and study the epidemiological data in each individual country and decide on the consensus guidelines on how the varicella vaccination can be targeted for those at risk.

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Asia Pacific Family Medicine
Asia Pacific Family Medicine Medicine-Family Practice
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