[(增加)肿瘤科临床药师的价值和老年患者潜在不当用药评估工具适用性的优化(药物负担指数和戴比尔斯标准)]。

Journal de pharmacie de Belgique Pub Date : 2014-03-01
J Van Den Broucke, A Verhaeghe, P R Debruyne, K Verhelle
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引用次数: 0

摘要

在一个试点项目中,检验了肿瘤科临床药师的价值。特别要注意的是关于在这一人群中使用可能不适当的药物的两个临床药学标准。首先是药物负担指数(Drug Burden Index, DBI),衡量个体对抗胆碱能药物和镇静药物的暴露程度。其次,比尔斯标准,一个明确的标准,潜在的不当使用药物的老年患者。根据比利时的实际情况,对标准进行了调整。由此可见,临床药师可以支持肿瘤患者的多学科治疗。在评估药物对肿瘤老年患者功能结局和认知的临床影响及其与硬终点的相关性时,上述两个标准的使用仍需进一步研究。
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[(Added) Value of a clinical pharmacist in the oncology department and optimalisation of the applicability of geriatric tools assessing potential inappropriate medication use in geriatric patients (Drug Burden Index and de Beers criteria)].

In a pilot project, the value of a clinical pharmacist in the oncology department is examined. There is special attention given to two clinical pharmaceutical criteria concerning use of potential inappropriate drugs in this population. First of all, the Drug Burden Index (DBI), a measurement of the individual exposure to anticholinergic and sedative drugs. Second of all, the Beers criteria, an explicit criterion of potential inappropriate use of drugs by the geriatric patient. Criteria are adapted for application in Belgian practice. It can be concluded that the clinical pharmacist can be used to support the multidisciplinary approach to cancer patients. The use of the two criteria mentioned above in the estimation of the clinical impact of drugs on functional outcome and cognition on the (oncolgeriatric patient and the correlation with hard endpoints, still need to be investigated.

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