人类蛋白ALX4、ZHX1和CASP8AP2同源结构域的溶液核磁共振结构有助于人类癌症蛋白相互作用网络的结构覆盖。

Xianzhong Xu, Surya V S R K Pulavarti, Alexander Eletsky, Yuanpeng Janet Huang, Thomas B Acton, Rong Xiao, John K Everett, Gaetano T Montelione, Thomas Szyperski
{"title":"人类蛋白ALX4、ZHX1和CASP8AP2同源结构域的溶液核磁共振结构有助于人类癌症蛋白相互作用网络的结构覆盖。","authors":"Xianzhong Xu,&nbsp;Surya V S R K Pulavarti,&nbsp;Alexander Eletsky,&nbsp;Yuanpeng Janet Huang,&nbsp;Thomas B Acton,&nbsp;Rong Xiao,&nbsp;John K Everett,&nbsp;Gaetano T Montelione,&nbsp;Thomas Szyperski","doi":"10.1007/s10969-014-9184-z","DOIUrl":null,"url":null,"abstract":"<p><p>High-quality solution NMR structures of three homeodomains from human proteins ALX4, ZHX1 and CASP8AP2 were solved. These domains were chosen as targets of a biomedical theme project pursued by the Northeast Structural Genomics Consortium. This project focuses on increasing the structural coverage of human proteins associated with cancer. </p>","PeriodicalId":73957,"journal":{"name":"Journal of structural and functional genomics","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10969-014-9184-z","citationCount":"1","resultStr":"{\"title\":\"Solution NMR structures of homeodomains from human proteins ALX4, ZHX1, and CASP8AP2 contribute to the structural coverage of the Human Cancer Protein Interaction Network.\",\"authors\":\"Xianzhong Xu,&nbsp;Surya V S R K Pulavarti,&nbsp;Alexander Eletsky,&nbsp;Yuanpeng Janet Huang,&nbsp;Thomas B Acton,&nbsp;Rong Xiao,&nbsp;John K Everett,&nbsp;Gaetano T Montelione,&nbsp;Thomas Szyperski\",\"doi\":\"10.1007/s10969-014-9184-z\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>High-quality solution NMR structures of three homeodomains from human proteins ALX4, ZHX1 and CASP8AP2 were solved. These domains were chosen as targets of a biomedical theme project pursued by the Northeast Structural Genomics Consortium. This project focuses on increasing the structural coverage of human proteins associated with cancer. </p>\",\"PeriodicalId\":73957,\"journal\":{\"name\":\"Journal of structural and functional genomics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2014-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1007/s10969-014-9184-z\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of structural and functional genomics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s10969-014-9184-z\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2014/6/19 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of structural and functional genomics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s10969-014-9184-z","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2014/6/19 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

对人蛋白ALX4、ZHX1和CASP8AP2三个同源结构域的高质量溶液NMR结构进行了解析。这些领域被选为东北结构基因组学联盟追求的生物医学主题项目的目标。这个项目的重点是增加与癌症相关的人类蛋白质的结构覆盖范围。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

摘要图片

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Solution NMR structures of homeodomains from human proteins ALX4, ZHX1, and CASP8AP2 contribute to the structural coverage of the Human Cancer Protein Interaction Network.

High-quality solution NMR structures of three homeodomains from human proteins ALX4, ZHX1 and CASP8AP2 were solved. These domains were chosen as targets of a biomedical theme project pursued by the Northeast Structural Genomics Consortium. This project focuses on increasing the structural coverage of human proteins associated with cancer.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Structural Genomics: General Applications Classification of ligand molecules in PDB with graph match-based structural superposition HOMCOS: an updated server to search and model complex 3D structures. NLDB: a database for 3D protein-ligand interactions in enzymatic reactions. Toward the next step in G protein-coupled receptor research: a knowledge-driven analysis for the next potential targets in drug discovery
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1