男性和绝经后妇女双酚a暴露与循环性激素浓度的关系。

Mian Li, Tian Ge Wang, Yu Xu, Jie Zhang, Bai Hui Xu, Min Xu, Yu Hong Chen, Jie Li Lu, Yu Fang Bi, Wei Qing Wang, Yan Yun Gu, Guang Ning
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引用次数: 1

摘要

本研究共招募了1116名中老年男性和1442名绝经后女性。研究了双酚A暴露是否与循环性激素浓度有关。单因素分析显示,尿双酚A浓度与血清黄体生成素水平呈负相关(β=-0.061, P
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Association of bisphenol a exposure with circulating sex hormone concentrations in men and postmenopausal women.

A total of 1116 middle-aged and elderly men and 1442 postmenopausal women were recruited in this study. Whether bisphenol A exposure was associated with circulating sex hormone concentrations was studied. Univariate analysis revealed that the urinary bisphenol A concentration was negatively correlated with the serum levels of luteinizing hormone (β=-0.061, P<0.0001) and follicle-stimulating hormone (β=-0.086, P<0.0001) in men, and with the serum levels of follicle-stimulating hormone (β=-0.037, P=0.018) and sex hormone-binding globulin (β=-0.043, P=0.006) in women. However, no significant association was observed between the serum levels of urinary bisphenol A and circulating sex hormone after adjustment for the potential confounders.

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