儿童哮喘的补充和替代药物:证据和专利概述。

IF 4.2 Q3 Pharmacology, Toxicology and Pharmaceutics Recent patents on inflammation & allergy drug discovery Pub Date : 2015-01-01 DOI:10.2174/1872213x09666150302105225
Kam-Lun E Hon, Ching Ki Fung, Alexander K C Leung, Theresa Ngan-Ho Leung, Daniel K K Ng
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引用次数: 14

摘要

哮喘是一种常见的儿童特应性疾病,与生活质量的显著损害有关。管理依赖于避免触发因素,如食物和空气过敏原,使用吸入支气管扩张剂/皮质类固醇和抗过敏或免疫调节疗法。吸入皮质类固醇(ICSs)和支气管扩张剂一直是主要的治疗方法。在中国和整个亚洲,对西医和皮质类固醇的误解和误解普遍存在,导致治疗不坚持。各种各样的补充和替代药物(CAM)是可用的。其中一些已经经过了广泛的临床试验,并被证明对哮喘有一定的治疗效果。然而,这些治疗方式大多无效,甚至可能有害。这篇文章概述了证据的临床疗效的所有主要CAM模式。尽管CAM模式被哮喘患者广泛使用,但很少有CAM专利可用。本文还讨论了最近与哮喘有关的专利。只有少数治疗哮喘的草药专利得到了评估,但治疗效果并没有实质性的记录。寻求CAM治疗哮喘的家长在使用之前必须咨询合格的注册医生。
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Complementary and alternative medicine for childhood asthma: an overview of evidence and patents.

Asthma is a prevalent childhood atopic disease associated with significant impairment of quality of life. Management relies on avoidance of triggers such as food and aeroallergens, the use of inhaled bronchodilators/corticosteroids and anti-allergic or immune-modulating therapies. Inhaled corticosteroids (ICSs) and bronchodilators have been the mainstay of treatment. In China as well as throughout Asia, myths and misconceptions on western medicine and corticosteroids are prevalent and result in non-adherence of treatment. A wide variety of complementary and alternative medicines (CAM) are available. Some of these have undergone extensive clinical trials and have been documented to have some therapeutic effects on asthma. Nevertheless, the majority of these treatment modalities is not efficacious and may even be detrimental. This article overviews the evidence for the clinical efficacy of all major CAM modalities. Despite CAM modalities are extensively used by the patients with asthma, very few CAM patents are available. This article also discusses recent patents pertinent to asthma. Only a few patents on herbal medicine for asthma have been evaluated but therapeutic efficacy is not substantially documented. Parents seeking CAM for asthma must consult qualified registered practitioners before using it.

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来源期刊
CiteScore
3.90
自引率
0.00%
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期刊介绍: Recent Patents on Inflammation & Allergy Drug Discovery publishes review articles by experts on recent patents in the field of inflammation and allergy drug discovery e.g. on novel bioactive compounds, analogs and targets. A selection of important and recent patents in the field is also included in the journal. The journal is essential reading for all researchers involved in inflammation and allergy drug design and discovery.
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