Pablo I Altieri, José M Marcial, Héctor L Banchs, Nelson Escobales, María Crespo, Wilma González
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Coronary levels of angiotensin-II and endothelin-I in diabetic patients with and without coronary artery disease.
Two groups of patients were studied to find out the levels of angiotensin-II and endothelin-I in the coronary and peripheral circulation. Group A consisted of eight patients with diabetes mellitus type 2 and coronary artery disease; and Group B with diabetes mellitus without coronary artery disease. Significant differences were found between Group A and B in the levels of both peptides peripherally and intracoronary. This shows the importance of these peptides in the origin of coronary artery disease and progression of the disease in diabetics with coronary artery disease.
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