巨大皮肤恶性黑色素瘤病例报告及文献综述:是什么让患者远离?

Eplasty Pub Date : 2022-09-23 eCollection Date: 2022-01-01
Jamie A Mawhinney, Adrien Yvon, Shahid Masood
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引用次数: 0

摘要

背景。巨大皮肤恶性黑色素瘤(MM)是一个术语,以前用于定义直径至少10厘米或厚度至少48毫米的病变。这种肿瘤很少见。没有大量的证据表明为什么MM患者会延迟出现,直到他们达到这个大小。本病例报告是迄今为止最大的巨大皮肤MM病例之一,也是文献中第一个显示对辅助免疫治疗有良好反应的病例。患者治疗成功,术后12个月仍然存活。对讨论巨型MM的文献进行了回顾,发现有必要对寻求医疗照顾的重要性进行教育,以预防晚期疾病,特别是对易受伤害的个体。
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Case Report and Literature Review of Giant Cutaneous Malignant Melanoma: What's Keeping Patients Away?

Background. Giant cutaneous malignant melanoma (MM) is a term that has previously been used to define lesions that are at least 10 cm in diameter or 48 mm in thickness. Such tumours are rare. There is no substantial body of evidence considering why patients may delay presentation with MM until they reach this size. This case report presents one of the largest cases of giant cutaneous MM to date and the first in the literature to show excellent response to adjuvant immunotherapy. The patient was treated successfully and remains alive and well 12 months following initial surgery. A review of the literature discussing giant MM identified a significant need for education on the importance of seeking medical attention in order to prevent advanced disease, especially for vulnerable individuals.

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