人类微生物组:从浴室到床边。

Stephen Malnick, Ehud Melzer
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引用次数: 13

摘要

人体肠道含有数万亿的细菌,其中主要的门包括拟杆菌门、厚壁菌门、放线菌门和变形菌门。粪便微生物移植(FMT)已被认识多年,但直到最近才受到严格的审查。我们回顾了关于FMT治疗复发性艰难梭菌感染的证据,这使得它成为一种被批准的治疗方法。此外,有一些证据表明它在肠易激综合征和炎症性肠病中都有使用。为了确定FMT的适应症和最合适的给药方法,需要进一步的研究。
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Human microbiome: From the bathroom to the bedside.

The human gut contains trillions of bacteria, the major phylae of which include Bacteroidetes, Firmicutes, Actinobacteria and Proteobacteria. Fecal microbial transplantation (FMT) has been known of for many years but only recently has been subjected to rigorous examination. We review the evidence regarding FMT for recurrent Clostridium difficile infection which has resulted in it being an approved treatment. In addition there is some evidence for its use in both irritable bowel syndrome and inflammatory bowel disease. Further research is needed in order to define the indications for FMT and the most appropriate method of administration.

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