[银纳米复合材料对大鼠脑组织的影响]。

E A Titov, L M Sosedova, M A Novikov
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引用次数: 0

摘要

本文介绍了用阿拉伯半乳聚糖聚合物基质包封银纳米粒子给药的实验材料。动物分别注射“纯”阿拉伯半乳聚糖和含有巨形银的胶体银溶液进行比较。研究提供了这些物质对机体影响时脑组织状态的数据。组织学分析显示病理过程的存在,其特征和强度取决于注射材料的类型。银阿拉伯半乳聚糖作用下的病理过程以脑组织血管周围水肿的出现和急性炎症的发展为特征,形成胶质瘢痕,血管束肿胀。
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[Alteration of white rats brain tissue inducted by assessment of silver nanocomposite incapsulated in polymer matrix].

The paper present experimental materials of intragastric administration of silver nanoparticles encapsulated in polymer matrix of arabinogalactan by white outbred male rats. Animals were injected "pure" arabinogalactan and colloid silver solution containing silver macroform separately for comparison. Research provided data about status of brain tissue at the impact of these substances on organism. Histological analysis revealed the presence of a pathological process, character and intensity of which varied depending on the type of injected material. Pathological process under the influence of silver-arabinogalactan characterized by appearance in brain tissue of perivascular edema and development of acute inflammation in formation of glial scars, swelling of vascular bundles in sum.

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