[长时间航天飞行后恢复期c57bl /6小鼠空肠黏膜固有层细胞组成]。

G G Aminova
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引用次数: 0

摘要

在30天的太空飞行7天后,对C57 BL/6小鼠(n = 5)和对照组动物(n = 6)的空肠进行了检查,并采用组织学和形态计量学方法研究了绒毛和隐窝区粘膜固有层的细胞组成。发现第7天固有层的正常细胞组成恢复不完全。绒毛内中小淋巴细胞数量减少,浆细胞数量减少。在隐窝区,这种变化不那么明显。实验动物固有层中大淋巴细胞、巨噬细胞、中性粒细胞、崩解细胞和基质细胞数量增多。嗜酸性粒细胞数量减少。
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[CELLULAR COMPOSITION OF THE LAMINA PROPRIA OF JEJUNAL MUCOUS MEMBRANE IN C57BL/6 MICE DURING THE RECOVERY PERIOD AFTER PROLONGED SPACE FLIGHT].

The jejunum of C57 BL/6 mice (n = 5) was examined 7 days after a 30-day-long space flight and in vivarium control animals (n = 6). The cellular composition of the lamina propria of the mucous membranes of the villi and crypt region was studied using histological and morphometric methods. It was found that on Day 7 the recovery of normal cellular composition of the lamina propria was incomplete. In the villi, the number of medium and small lymphocytes, as well as of the plasma cells was reduced. In the crypt region, the changes were less pronounced. In the lamina propria in experimental animals the number of large lymphocytes, macrophages, neutrophils, disintegrating cells and stromal cells was increased. The number of eosinophils was reduced.

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