澳大利亚脑膜炎球菌监测规划年度报告,2014年。

IF 1.6 Q4 INFECTIOUS DISEASES Communicable Diseases Intelligence Pub Date : 2016-06-30
Monica M Lahra, Rodney P Enriquez
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引用次数: 0

摘要

2014年,澳大利亚国家奈瑟菌网络分析了165例经实验室确认的侵袭性脑膜炎球菌病病例。这一数字高于2013年报告的数字,但是自1994年澳大利亚脑膜炎球菌监测规划启动以来报告的第二低数字。在澳大利亚,可能的和实验室确认的侵袭性脑膜炎球菌病(IMD)是必须报告的,2014年有170例IMD病例报告给国家法定疾病监测系统(NNDSS)。这一数字也高于2013年,但是NNDSS报告的IMD病例数第二低的年份。在161/165(98%)实验室确诊的IMD病例中测定了脑膜炎球菌血清组。其中80.1%(129例)为血清B组感染;血清C组感染3例,占1.9%;9.9%(16例)为W135血清组;血清y组13例,占8.1%。4岁以下和15 ~ 19岁的青少年分别为原发性和继发性发病高峰。血清B组病例在所有辖区和年龄组中占主导地位,但65岁或以上的人群除外,其中血清Y组和W135组合并占主导地位。血清B组所致IMD的总体比例和数量均高于2013年,但较前几年有所下降。由血清C组引起的IMD病例数是迄今为止报告的最少的。Y型血清引起的IMD病例数与往年相似,但W135型血清引起的IMD病例数高于2013年。近年来,由Y和W135血清组引起的IMD病例所占比例有所上升,而IMD的总病例数却有所下降。165例IMD病例中有106例可以进行分子分型。2014年澳大利亚流行的最常见的porA基因型为p1.7 -2,4和p1.22,14。所有IMD分离株均对头孢曲松和环丙沙星敏感。有2株菌株对利福平耐药。88%的分离株对青霉素的敏感性降低。
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Australian Meningococcal Surveillance Programme annual report, 2014.

In 2014 there were 165 laboratory-confirmed cases of invasive meningococcal disease analysed by the Australian National Neisseria Network. This number was higher than the number reported in 2013, but was the second lowest reported since inception of the Australian Meningococcal Surveillance Programme in 1994. Probable and laboratory confirmed invasive meningococcal disease (IMD) are notifiable in Australia, and there were 170 IMD cases notified to the National Notifiable Diseases Surveillance System (NNDSS) in 2014. This was also higher than in 2013, but was the second lowest number of IMD cases reported to the NNDSS. The meningococcal serogroup was determined for 161/165 (98%) of laboratory confirmed IMD cases. Of these, 80.1% (129 cases) were serogroup B infections; 1.9% (3 cases) were serogroup C infections; 9.9% (16 cases) were serogroup W135; and 8.1% (13 cases) were serogroup Y. Primary and secondary disease peaks were observed in those aged 4 years or less, and in adolescents (15-19 years) respectively. Serogroup B cases predominated in all jurisdictions and age groups, except for those aged 65 years or over, where serogroups Y and W135 combined predominated. The overall proportion and number of IMD caused by serogroup B was higher than in 2013, but has decreased from previous years. The number of cases of IMD caused by serogroup C was the lowest reported to date. The number of IMD cases caused by serogroup Y was similar to previous years, but the number of IMD cases caused serogroup W135 was higher than in 2013. The proportion of IMD cases caused by serogroups Y and W135 has increased in recent years, whilst the overall number of cases of IMD has decreased. Molecular typing was able to be performed on 106 of the 165 IMD cases. In 2014, the most common porA genotypes circulating in Australia were P1.7-2,4 and P1.22,14. All IMD isolates tested were susceptible to ceftriaxone and ciprofloxacin. There were 2 isolates that were resistant to rifampicin. Decreased susceptibility to penicillin was observed in 88% of isolates.

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Communicable Diseases Intelligence
Communicable Diseases Intelligence INFECTIOUS DISEASES-
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Professor Mary-Louise McLaws (17 March 1953 – 12 August 2023) Summary of National Surveillance Data on Vaccine Preventable Diseases in Australia, 2016-2018 Final Report - Erratum to Commun Dis Intell (2018) 2022;46. (https://doi.org/10.33321/cdi.2022.46.28) COVID-19 Australia: Epidemiology Report 73 Reporting period ending 9 April 2023 Australian Rotavirus Surveillance Program: Annual Report, 2017 Invasive Pneumococcal Disease Surveillance, 1 January to 31 March 2017.
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