造影剂引起的急性肾损伤:实用要点综述。

Sercin Ozkok, Abdullah Ozkok
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引用次数: 108

摘要

造影剂引起的急性肾损伤(CI-AKI)是临床上最常见的AKI病因之一。CI-AKI已被发现与患者的发病率和死亡率密切相关。此外,CI-AKI可能并不总是可逆的,它可能与慢性肾脏疾病的发展有关。CI-AKI的病理生理机制尚不完全清楚,对预防策略也没有共识。CI-AKI是一个活跃的研究领域,因此临床医生应该定期更新这一主题。在这篇综述中,我们旨在讨论对比增强成像的适应症,造影剂的类型及其对肾毒性的影响,CI-AKI的主要病理生理机制,危险因素和预防策略,以及替代的非对比增强成像方法。
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Contrast-induced acute kidney injury: A review of practical points.

Contrast-induced acute kidney injury (CI-AKI) is one of the most common causes of AKI in clinical practice. CI-AKI has been found to be strongly associated with morbidity and mortality of the patients. Furthermore, CI-AKI may not be always reversible and it may be associated with the development of chronic kidney disease. Pathophysiology of CI-AKI is not exactly understood and there is no consensus on the preventive strategies. CI-AKI is an active research area thus clinicians should be updated periodically about this topic. In this review, we aimed to discuss the indications of contrast-enhanced imaging, types of contrast media and their impact on nephrotoxicity, major pathophysiological mechanisms, risk factors and preventive strategies of CI-AKI and alternative non-contrast-enhanced imaging methods.

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