多发性硬化症药物治疗的视觉后果:好的、坏的、丑陋的和未知的。

IF 3.1 Q1 OPHTHALMOLOGY Eye and Brain Pub Date : 2017-06-29 eCollection Date: 2017-01-01 DOI:10.2147/EB.S140481

Heather E Moss

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引用次数: 14

摘要

多发性硬化症(MS)与视觉变化有关，这是由于MS对视觉通路的影响以及药物对视觉通路的影响。辨别视力改变的原因对适当的诊断和治疗至关重要。本文综述了多发性硬化症患者中fingolimod相关黄斑水肿、阿仑单抗相关甲状腺眼窝病和进行性多灶性脑白质病的发病率、表现和治疗。证据表明，急性、慢性和症状性MS药物对视力有有益影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Visual consequences of medications for multiple sclerosis: the good, the bad, the ugly, and the unknown.

Multiple sclerosis (MS) is associated with vision changes both due to MS effects on visual pathways and due to medication effects on the visual pathways. Distinguishing the causes of vision change are critical to appropriate diagnosis and management. The incidence, presentation, and treatment of fingolimod-associated macular edema, alemtuzumab-associated thyroid orbitopathy, and progressive multifocal leukoencephalopathy in MS patients are reviewed. Evidence for beneficial effects of acute, chronic, and symptomatic MS medications on vision is presented.

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来源期刊

Eye and Brain OPHTHALMOLOGY-

CiteScore

7.90

自引率

2.30%

发文量

审稿时长

16 weeks

期刊介绍： Eye and Brain is an international, peer-reviewed, open access journal focusing on basic research, clinical findings, and expert reviews in the field of visual science and neuro-ophthalmology. The journal’s unique focus is the link between two well-known visual centres, the eye and the brain, with an emphasis on the importance of such connections. All aspects of clinical and especially basic research on the visual system are addressed within the journal as well as significant future directions in vision research and therapeutic measures. This unique journal focuses on neurological aspects of vision – both physiological and pathological. The scope of the journal spans from the cornea to the associational visual cortex and all the visual centers in between. Topics range from basic biological mechanisms to therapeutic treatment, from simple organisms to humans, and utilizing techniques from molecular biology to behavior. The journal especially welcomes primary research articles or review papers that make the connection between the eye and the brain. Specific areas covered in the journal include: Physiology and pathophysiology of visual centers, Eye movement disorders and strabismus, Cellular, biochemical, and molecular features of the visual system, Structural and functional organization of the eye and of the visual cortex, Metabolic demands of the visual system, Diseases and disorders with neuro-ophthalmic manifestations, Clinical and experimental neuro-ophthalmology and visual system pathologies, Epidemiological studies.