动态预算分配的HIV预防数值最优控制。

IF 0.8 4区数学 Q4 BIOLOGY Mathematical Medicine and Biology-A Journal of the Ima Pub Date : 2018-12-05 DOI:10.1093/imammb/dqx015

Dmitry Gromov, Ingo Bulla, Oana Silvia Serea, Ethan O Romero-Severson

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引用次数: 12

摘要

这篇文章是关于艾滋病毒传播的数控。本文的贡献有三个方面:首先，提出了一种新的HIV传播模型;其次，将数值最优控制方法成功地应用于所建立的模型，计算最优控制曲线;最后，将计算结果应用于实际问题，得到了重要的、具有实际意义的结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Numerical optimal control for HIV prevention with dynamic budget allocation.

This article is about numerical control of HIV propagation. The contribution of the article is threefold: first, a novel model of HIV propagation is proposed; second, the methods from numerical optimal control are successfully applied to the developed model to compute optimal control profiles; finally, the computed results are applied to the real problem yielding important and practically relevant results.

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来源期刊

Mathematical Medicine and Biology-A Journal of the Ima 生物-生物学

CiteScore

2.20

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Formerly the IMA Journal of Mathematics Applied in Medicine and Biology. Mathematical Medicine and Biology publishes original articles with a significant mathematical content addressing topics in medicine and biology. Papers exploiting modern developments in applied mathematics are particularly welcome. The biomedical relevance of mathematical models should be demonstrated clearly and validation by comparison against experiment is strongly encouraged. The journal welcomes contributions relevant to any area of the life sciences including: -biomechanics- biophysics- cell biology- developmental biology- ecology and the environment- epidemiology- immunology- infectious diseases- neuroscience- pharmacology- physiology- population biology