干细胞移植中的移植物抗宿主病。

Duodecim; laaketieteellinen aikakauskirja Pub Date : 2017-01-01

Mervi Taskinen, Samppa Ryhänen, Kim Vettenranta

{"title":"干细胞移植中的移植物抗宿主病。","authors":"Mervi Taskinen, Samppa Ryhänen, Kim Vettenranta","doi":"","DOIUrl":null,"url":null,"abstract":"Graft-versus-host disease (GvHD) remains a major treatment-related risk in patients undergoing stem cell transplantation. Although advances in HLA-typing and graft types have reduced the risk of GvHD, a breakthrough in the treatment of severe GvHD is still lacking. Allogenic stem cell transplant has potentially beneficial immunological effects on the malignant disease necessitating transplantation, and the importance of these effects must be considered when treating GvHD.","PeriodicalId":72850,"journal":{"name":"Duodecim; laaketieteellinen aikakauskirja","volume":"133 3","pages":"251-8"},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Graft-versus-host disease in stem cell transplantation.\",\"authors\":\"Mervi Taskinen, Samppa Ryhänen, Kim Vettenranta\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Graft-versus-host disease (GvHD) remains a major treatment-related risk in patients undergoing stem cell transplantation. Although advances in HLA-typing and graft types have reduced the risk of GvHD, a breakthrough in the treatment of severe GvHD is still lacking. Allogenic stem cell transplant has potentially beneficial immunological effects on the malignant disease necessitating transplantation, and the importance of these effects must be considered when treating GvHD.\",\"PeriodicalId\":72850,\"journal\":{\"name\":\"Duodecim; laaketieteellinen aikakauskirja\",\"volume\":\"133 3\",\"pages\":\"251-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Duodecim; laaketieteellinen aikakauskirja\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Duodecim; laaketieteellinen aikakauskirja","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

移植物抗宿主病(GvHD)仍然是干细胞移植患者的主要治疗相关风险。尽管hla分型和移植物类型的进步降低了GvHD的风险，但在治疗严重GvHD方面仍然缺乏突破。同种异体干细胞移植对需要移植的恶性疾病具有潜在的有益免疫作用，在治疗GvHD时必须考虑到这些作用的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Graft-versus-host disease in stem cell transplantation.

Graft-versus-host disease (GvHD) remains a major treatment-related risk in patients undergoing stem cell transplantation. Although advances in HLA-typing and graft types have reduced the risk of GvHD, a breakthrough in the treatment of severe GvHD is still lacking. Allogenic stem cell transplant has potentially beneficial immunological effects on the malignant disease necessitating transplantation, and the importance of these effects must be considered when treating GvHD.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助