黑草根的生药学和植物化学研究。

V Kishor Kumar, K G Lalitha
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引用次数: 5

摘要

背景:黑Helleborus niger L(毛茛科)被用于阿育吠陀和乌纳尼系统和其他草药系统。黑根具有很好的药用价值。目的:对黑螺旋藻进行生药学和植物化学研究。材料与方法:建立了根的生药学研究,包括分类、宏观、微观特征、理化、紫外分析和植物化学研究等参数。结果:宏观上,根呈棕黑色,形状呈圆柱形,气味微弱,味微涩,分枝不规则。显微镜下,根有表皮、气室、裂周皮、周皮、内皮层、髓、韧皮部、木质部、导管和木质部导管。显微检查显示,粉末中有薄壁细胞、薄壁团块、周皮、细胞包涵体、乳汁管、侧壁髓、穿孔、木质部束和木质部分子。用不同的试剂进行了紫外和普通光分析,以鉴别粉末形式的药物。建立理化评价,总灰分、酸不溶灰分、水溶性灰分和硫酸盐灰分值分别为7.3%、4.1%、3.7%和5.2%。醇溶性、水溶性和醚溶性萃取物的萃取值分别为22.8%、7.4%和5.6%。干燥损失为3.3%。初步的植物化学筛选表明,其中含有碳水化合物、糖苷、皂苷、类黄酮、植物甾醇、单宁和酚类化合物。结论:本研究结果可作为一种有价值的生药学和植物化学信息资源。这将作为在未来研究和应用中发现该植物材料的适当标准,并有助于建立药典标准。
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Pharmacognostical and Phytochemical Studies of Helleborus niger L Root.

Background: Helleborus niger L (Ranunculaceae) is used Ayurvedic and Unani systems and other herbal medicine systems. The roots of H. niger have a good medicinal value.

Aims: To conduct a pharmacognostical and phytochemical study of H. niger.

Materials and methods: The pharmacognostical studies on roots including parameters such as taxonomical, macroscopic, microscopic characters, physico-chemical, ultra-violet analysis and phytochemical studies are established.

Results: Macroscopically, the roots are brownish-black in colour, cylindrical in shape, feeble odour, slightly acrid taste with irregularly branched. Microscopically the root showed the presence of epidermis, air-chambers, fissure periderm, periderm, inner cortex, pith, phloem, xylem, vessels and xylem vessels. Microscopic examination of the powder showed the presence of parenchyma cells, parenchyma mass, periderm, cell inclusion, laticifer, lateral wall pith, perforation, xylem bundle and xylem elements. Ultra-violet and ordinary light analyses with different reagents were conducted to identify the drug in powder form. Physico-chemical evaluation established, Ash values - Total, acid insoluble, water soluble and sulphated ash values were 7.3%, 4.1%, 3.7% and 5.2%, respectively. Extractive values - Alcohol soluble, water soluble and ether soluble extractive values were 22.8%, 7.4% and 5.6%, respectively. Loss on drying was 3.3%. Preliminary phytochemical screening showed the presence of carbohydrate, glycoside, saponins, flavonoid, phytosterols, tannins and phenolic compounds.

Conclusions: The results of the study can serve as a valuable resource of pharmacognostic and phytochemical information. This will serve as appropriate, standards for discovery of this plant material in future investigations and applications and also contribute towards establishing pharmacopoeial standards.

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